Results 241 to 250 of about 1,323,303 (307)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Ecological integrity as a foundation for European health policy. [PDF]

open access: yesLancet Reg Health Eur
Biller-Andorno N   +2 more
europepmc   +1 more source

Impedance Spectroscopy Analysis of Field-Assisted Sintered Sr- and Mg-Doped Lanthanum Gallate. [PDF]

open access: yesMaterials (Basel)
Reis SL   +5 more
europepmc   +1 more source

Understanding the Boundaries of Empathy: A Qualitative Exploration in Pediatric Oncology Nursing. [PDF]

open access: yesChildren (Basel)
Aydın A   +4 more
europepmc   +1 more source

A Multi-Stage Drop-the-Loser Design With Superiority Boundaries. [PDF]

open access: yesStat Med
Greenstreet P   +6 more
europepmc   +1 more source

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