Results 141 to 150 of about 647,771 (267)

An Inverse Signorini Obstacle Problem. [PDF]

Arch Ration Mech Anal
de Hoop MV, Lassas M, Lu J, Oksanen L, Zhao Z.   +4 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Single-Criterion Optimisation with Consideration of Uncertainties of the Composite Multi-Layer Slabs. [PDF]

Materials (Basel)
Smela P, Miller B.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Trade-Offs of Conservation Fencing in Western Serengeti: Enhancing Agricultural Security While Navigating Unintended Consequences on Land-Use Dynamics. [PDF]

Ecol Evol
Kimaro MH, Sloots MI, Snyder KD, Mbise NL, Kakengi VA, Di Nicola W, Olff H.   +6 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Boundary-Sensitive Hybrid Attention Network for Multi-Scale Crack Fine Segmentation. [PDF]

Sensors (Basel)
Jiang Y, Wang T, Shao C, Chen X, Liang J.   +4 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Trace theory for parabolic boundary value problems with rough boundary conditions. [PDF]

J Evol Equ
Denk R, Roodenburg FB.
europepmc   +1 more source

On the formation of boundary conditions on the outer boundary of a boundary layer [PDF]

Engineering Journal: Science and Innovation, 2013
openaire   +1 more source