Results 41 to 50 of about 23,409 (291)

Three-dimensional BEM for transient dynamic analysis of piezoelectric and anisotropic elastic solids

open access: yesEPJ Web of Conferences, 2015
A boundary element approach based on the Green's functions in integral representation and the convolution quadrature method is presented. Proposed approach is designed for analyzing 3D initial boundary-value problems of the dynamics of general ...
Igumnov Leonid   +4 more
doaj   +1 more source

Method for solving plane unsteady contact problems for rigid stamp and elastic half-space with a cavity of arbitrary geometry and location [PDF]

open access: yesINCAS Bulletin, 2020
In the work, the process of unsteady contact interaction of rigid stamp and elastic half-space having a recessed cavity of arbitrary geometry and location with a smooth boundary was investigated.
Yulong LI   +3 more
doaj   +1 more source

A Nystr�m method for boundary integral equations in domains with corners

open access: yesNumerische Mathematik, 1990
The core of this work is a high order quadrature formula for integrals with endpoint singularities. The author obtains such a formula using the trapezoidal rule for the transformed integral. This quadrature rule is then applied in the Nyström method for a class of integral equations of the second kind with endpoint singularities. Finally, the method is
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

DBEM solutions to modified Helmholtz problems for FGMs of space–time-dependent properties

open access: yesResults in Physics
A combined Laplace transform (LT) and domain-boundary element method (DBEM) are utilized to obtain numerical solutions for a spatio-temporal coefficient modified Helmholtz-type equation with arbitrary initial conditions and source terms, addressing ...
Mohammad Ivan Azis
doaj   +1 more source

Computing Robin Problem on Unbounded Simply Connected Domain via an Integral Equation with the Generalized Neumann Kernel

open access: yesKurdistan Journal of Applied Research, 2017
A Robin problem is a mixed problem with a linear combination of Dirichlet and Neumann D-N conditions. The aim of this paper are presents a new boundary integral equation BIE method for the solution of unbounded Robin boundary value problem BVP in the ...
Shwan H. H. Al-Shatri   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Boundary Element Modeling of Dynamic Bending of a Circular Piezoelectric Plate

open access: yesEPJ Web of Conferences, 2018
Accurate modelling of a coupled dynamic electro-mechanical response of circular piezoelectric plates under various loading conditions is of particular importance.
Igumnov Leonid   +2 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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