Results 181 to 190 of about 1,137,021 (285)

Material Fracturing and Failure Simulation Datasets. [PDF]

Sci Data
Hill RG, Gao K, Pachalieva A, Marcato A, Wang X, Grosset P, Rougier E, Lei Z, Santos JE, Agrawal V, Kang Q, Hyman JD, Hunter A, Sweeney CM, DeBardeleben N, Lawrence E, Viswanathan H, O'Malley D.   +17 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Research on the Coupled Bionic Design and Validation of Flying Car Folding Wings Based on Eurasian Eagle-Owl Wing Shape. [PDF]

Appl Bionics Biomech
Li Z, Cao Y, Zhao D.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Multi-Scale Modeling in Forming Limits Analysis of SUS430/Al1050/TA1 Laminates: Integrating Crystal Plasticity Finite Element with M-K Theory. [PDF]

Materials (Basel)
Li X, Liu C, Bai Y.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

On the Numerical Evaluation of Wall Shear Stress Using the Finite Element Method. [PDF]

Int J Numer Method Biomed Eng
Brunátová J, Dokken JS, Valen-Sendstad K, Hron J.   +3 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Optimization of the cut configuration for skin grafts. [PDF]

Biomech Model Mechanobiol
Harbrecht H, Karnaev V.
europepmc   +1 more source

Boundary-Element Method in Microfluidics [PDF]

, 2014
Çetin, Barbaros, Baranoğlu, B.
openaire   +2 more sources