Results 181 to 190 of about 215,554 (316)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Dual boundary element method for axisymmetric crack analysis
In this paper a dual boundary element formulation is developed and applied to the evaluation of stress intensity factors in, and propagation of, axisymmetric cracks.
Wrobel, LC, Lacerda, LA
core
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
An Adaptive Coupling of Edge-Based Smoothed FEM and SPH with a Bidirectional Element-Particle Transformation Algorithm for Laser Powder Bed Fusion. [PDF]
Suo M, Long T.
europepmc +1 more source
In this paper the hp-version of the boundary element method is applied to the electric field integral equation on a piecewise plane (open or closed) Lipschitz surface. The underlying meshes are supposed to be quasi-uniform.
Bespalov, A, Heuer, N
core
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Considering the uncertainty associated with structural boundary conditions, a method for modifying the boundary constraint static model of beam structures was proposed based on the homotopy stochastic finite element method.
HU Jianwei +5 more
doaj
A general numerical method is described for the solution of linear elliptic and parabolic partial differential equations in the presence of boundary singularities.
Furzeland, RM, Crank, J
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source

