Results 151 to 160 of about 268,935 (316)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

On boundary-value problems for generalized analytic and harmonic functions

open access: yesДоповiдi Нацiональної академiї наук України
The present paper is a natural continuation of our last articles on the Riemann, Hilbert, Dirichlet, Poincaré, and, in particular, Neumann boundary-value problems for quasiconformal, analytic, harmonic functions and the so-called A-harmonic functions ...
V.Ya. Gutlyanskiĭ   +3 more
doaj   +1 more source

Further numerical techniques for planar elastostatic analysis by the boundary integral equation method

open access: yes, 1984
Includes bibliography.Prior experience of the Finite Element Method stimulated interest and led to research into the Boundary Integral Equation Method, specifically for the solution of planar elastostatic problems.
Howell, Graham Conrad
core  

Bulk and boundary scattering in the q-state potts mode [PDF]

open access: yes, 1998
This thesis is concerned with the properties of 1 + 1 dimensional massive field theories in both infinite and semi-infinite geometries. Chapters 1, 2 and 3 develop the necessary theoretical framework and review existing work by Chim and Zamolodchikov [1]
Pocklington, Andrew Jonathan
core  

Boundary functions for functions defined in a disk.

open access: yesMichigan Mathematical Journal, 1961
Bagemihl, F., Piranian, G.
openaire   +2 more sources

On the Boundary Values of Harmonic Functions

open access: yesRevista Matemática Iberoamericana, 1985
Let D be a domain with smooth boundary \(\partial D\) in the Euclidean space of dimension \(n\geq 3\). Given a continuous function w on \(\partial D\) with a continuous extension to D having a finite Dirichlet integral, it is known that the Dirichlet solution in D of f is the orthogonal projection of w onto the Hilbert space H of harmonic functions in ...
openaire   +3 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

On the significance of form induced stress in rough wall turbulent boundary layers

open access: yes, 2008
This paper presents a review of recent experimental and numerical studies which deal with the analysis of form-induced stress in rough wall turbulent boundary layers.
Costantino Manes   +16 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Positive solutions for singular three-point boundary-value problems

open access: yesElectronic Journal of Differential Equations, 2007
In this paper, we present the Green's functions for a second-order linear differential equation with three-point boundary conditions. We give exact expressions of the solutions for the linear three-point boundary problems by the Green's functions.
Zengqin Zhao
doaj  

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