Results 41 to 50 of about 3,234,210 (272)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Existence of solutions to boundary value problem of fractional differential equations with impulsive
Journal of Hebei University of Science and Technology, 2016 In order to solve the boundary value problem of fractional impulsive differential equations with countable impulses and integral boundary conditions on the half line, the existence of solutions to the boundary problem is specifically studied. By defining
Weihua JIANG, Qingmin LI, Cailian ZHOU
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Boundary Integral Solutions of the Heat Equation [PDF]
Mathematics of Computation, 1986 The Boundary Integral Method (BIM) has recently become quite popular because of its ability to provide cheap numerical solutions to the Laplace equation. This paper describes an attempt to apply a similar approach to the (time-dependent) heat equation in two space variables.
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Analysis of some localized boundary-domain integral equations [PDF]
, 2009 Some direct segregated localized boundary-domain integral equation (LBDIE) systems associated with the Dirichlet and Neumann boundary value problems (BVP) for a scalar "Laplace" PDE with variable coefficient are formulated and analysed. The parametrix is
Mikhailov, SE +2 more
core +4 more sources
Математичні СтудіїWe consider approach based on the integral representation of solutions in domain which consists of bounded and unbounded parts that gives us opportunity to reduce different transmission type problems to connected with them equivalent boundary equations ...
Yu. M. Sybil
doaj +1 more source
Journal of Function Spaces, 2017 This paper deals with the integral boundary value problems of fractional differential equations at resonance. By Mawhin’s coincidence degree theory, we present some new results on the existence of solutions for a class of differential equations of ...
Yumei Zou, Guoping He
doaj +1 more source