Results 111 to 120 of about 6,143,947 (388)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Homogenization and boundary layers

open access: yes, 2012
This paper deals with the homogenization of elliptic systems with Dirichlet boundary condition, when the coefficients of both the system and the boundary data are e-periodic.
D. Gérard-Varet, N. Masmoudi
semanticscholar   +1 more source

Computation of turbulent boundary layers on curved surfaces, 1 June 1975 - 31 January 1976 [PDF]

open access: yes
An accurate method was developed for predicting effects of streamline curvature and coordinate system rotation on turbulent boundary layers. A new two-equation model of turbulence was developed which serves as the basis of the study.
Chambers, T. L., Wilcox, D. C.
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Studies on Ionic Flows via Poisson–Nernst–Planck Systems with Bikerman’s Local Hard-Sphere Potentials under Relaxed Neutral Boundary Conditions

open access: yesMathematics
We examine the qualitative properties of ionic flows through ion channels via a quasi-one-dimensional Poisson–Nernst–Planck model under relaxed neutral boundary conditions.
Xiangshuo Liu, Lijun Zhang, Mingji Zhang
doaj   +1 more source

Robust Error Estimation for Singularly Perturbed Fourth Order Problems

open access: yesМоделирование и анализ информационных систем, 2016
We consider two-dimensional singularly perturbed fourth order problems and estimate on properly constructed layer-adapted errors of a mixed method in the associated energy norms and balanced norms. This paper is a shortened version of [4].
S. Franz, R. H.-G.
doaj   +1 more source

Interplanetary boundary layers at 1 AU [PDF]

open access: yes
The structure and nature of discontinuities in the interplanetary magnetic field at 1 AU in the period March 18, 1971 to April 9, 1971, is determined by using high-resolution magnetic field measurements from Explorer 34.
Burlaga, L. F.   +2 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Analysis of Thermal and Roughness Effects on the Turbulent Characteristics of Experimentally Simulated Boundary Layers in a Wind Tunnel. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Demarco G   +11 more
europepmc   +1 more source

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