AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Conscious simultaneity with continuous motion: a measure-theoretic resolution of the hard problem. [PDF]
Sanfey J.
europepmc +1 more source
Stacking Pressure‐Driven Interfacial Dynamics in Anode‐Free Solid‐State Lithium Batteries
Using a three‐electrode setup, it is found that stacking pressure improves both anode and cathode interfaces but more effectively stabilizes the anode. Under low pressure, a sudden anode resistance rise indicates contact loss. Higher pressure delays this via Li creep and plastic deformation, maintaining interfacial contact.
Jianneng Liang +8 more
wiley +1 more source
Declaring Worldviews in SSM for Sustainability & Community Learning. [PDF]
Weaver MW +4 more
europepmc +1 more source
A Robotic Testing Platform for Pipelined Discovery of Resilient Dielectric Elastomer Actuators
This work introduces a robotic testing platform enabling high‐throughput, multi‐parameter lifetime mapping of linear dielectric elastomer actuators (DEAs). By integrating programmable high‐voltage control and automated electromechanical measurements, the system identifies material and operating conditions that double actuator lifetime.
Ang (Leo) Li +10 more
wiley +1 more source
Nonlinear Vibrations and Potential Instabilities of a Nanochassis Traveling a Route with Arbitrarily Tiny Irregularities. [PDF]
Xie B, Wu K, Nikkhoo A.
europepmc +1 more source
Butterfly wing–inspired intrinsically self‐healing polymer interlayers enable flexible perovskite optoelectronics with high luminance, strain‐insensitive stability, and environmental resilience. These hierarchically structured films redistribute mechanical stress, suppress defect formation, and maintain performance under repeated bending, paving the ...
Loganathan Veeramuthu +13 more
wiley +1 more source
Metasurface analogues of molecular diastereomers from hierarchical multiscale chiral interactions with biomolecules. [PDF]
Koyroytsaltis-McQuire DJP +11 more
europepmc +1 more source
Non‐Hermitian Stealthy Hyperuniformity
A framework for non‐Hermitian extensions of hyperuniformity and stealthiness is proposed, generalizing PT‐symmetric gain‐loss crystals to correlated disorder in the weak‐scattering limit. By engineering real‐imaginary correlations of the material potential, this framework enables directional scattering phases inaccessible in Hermitian materials ...
Gitae Lee +8 more
wiley +1 more source
Adjoint-based PDE-constrained optimization of viscoelastic floating membrane for maximum wave power absorption. [PDF]
El Sayed K +3 more
europepmc +1 more source

