Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Improved bounds for solutions of ϕ-Laplacians
Opuscula Mathematica, 2018 Summary: In this short paper we prove a parametric version of the Harnack inequality for \(\phi\)-Laplacian equations. In this sense, the estimates are optimal and represent an improvement of previous bounds for this kind of operators.
Waldo Arriagada, Jorge Huentutripay
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
On first-order differential operators with Bohr-Neugebauer type property
International Journal of Mathematics and Mathematical Sciences, 1989 We consider a differential equation ddtu(t)-Bu(t)=f(t), where the functions u and f map the real line into a Banach space X and B: X →X is a bounded linear operator.
Aribindi Satyanarayan Rao
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Bounded Approximate Decentralised Coordination via the Max-Sum Algorithm [PDF]
, 2011 In this paper we propose a novel approach to decentralised coordination, that is able to efficiently compute solutions with a guaranteed approximation ratio. Our approach is based on a factor graph representation of the constraint network.
Farinelli, A. +14 more
core +1 more source
Comparison of properties of solutions of differential equations and recurrence equations with the same characteristic equation (on example of third order linear equations with constant coefficients) [PDF]
Opuscula Mathematica, 2006 Third order linear homogeneous differential and recurrence equations with constant coefficients are considered. We take the both equations with the same characteristic equation.
Jarosław Mikołajski, Ewa Schmeidel
doaj
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Problem With Bounded Rationality On Behavioral Assumptions in the Theory of the Firm [PDF]
I discuss and compare alternative approaches to integrating bounded rationality with the theory of economic organization, concentrating on the organizational capabilities approach, which is strongly influenced by the works of Nelson and Winter ...
Nicolai J. Foss
core
Fixed Point Theory and Applications, 2011 In this paper, the existence, uniqueness and iterative approximations of fixed points for contractive mappings of integral type in complete metric spaces are established.
Kang Shin, Cho Sun, Liu Zeqing, Li Xin
doaj