Results 51 to 60 of about 3,031,442 (296)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Bounded solutions of nonlinear parabolic equations
Electronic Journal of Differential Equations, 2010 We are concerned with bounded solutions existing for all times for nonlinear parabolic equations with possibly nonlinear boundary conditions. A counterexample shows that, without an additional condition, a (weak) maximum principle does not hold for ...
Nsoki Mavinga, Mubenga N. Nkashama
doaj
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Determining the Best Algorithm for the Knapsack Problem with Forfeits
MathematicsIn 2024, four papers that presented four different solution approaches for the knapsack problem with forfeits (KPF) appeared in the OR literature. However, none of these four solution approaches compared their performance to the other three on a standard
Peter Cadiz +3 more
doaj +1 more source
Solution structures of DNA-bound gyrase [PDF]
Nucleic Acids Research, 2010 The DNA gyrase negative supercoiling mechanism involves the assembly of a large gyrase/DNA complex and conformational rearrangements coupled to ATP hydrolysis. To establish the complex arrangement that directs the reaction towards negative supercoiling, bacterial gyrase complexes bound to 137- or 217-bp DNA fragments representing the starting ...
Nicole M. Baker +3 more
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Bounds on the disparity and separation of tournament solutions
Discrete Applied Mathematics, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Felix Brandt 0001 +2 more
openaire +3 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Учёные записки Казанского университета: Серия Физико-математические наукиThis article explores the generalized Cauchy–Riemann system on the entire complex plane. The coefficient for the conjugation of the desired function belongs to the Hölder space and, for |z| > 1 , equals eimϕ , where m is an integer.
S. Baizaev, R. N. Barotov
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source