Results 51 to 60 of about 18,644 (317)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A note on the global existence and boundedness of an N-dimensional parabolic-elliptic predator-prey system with indirect pursuit-evasion interaction

open access: yesOpen Mathematics
We investigate the two-species chemotaxis predator-prey system given by the following system: ut=Δu−χ∇⋅(u∇w)+u(λ1−μ1ur1−1+av),x∈Ω,t>0,vt=Δv+ξ∇⋅(v∇z)+v(λ2−μ2vr2−1−bu),x∈Ω,t>0,0=Δw−w+v,x∈Ω,t>0,0=Δz−z+u,x∈Ω,t>0,\left\{\begin{array}{ll}{u}_{t}=\Delta u-\chi \
Liu Ling
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Boundedness in a quasilinear fully parabolic two-species chemotaxis system of higher dimension

open access: yesBoundary Value Problems, 2017
This paper considers the following coupled chemotaxis system: { u t = ∇ ⋅ ( ϕ ( u ) ∇ u ) − χ 1 ∇ ⋅ ( u ∇ w ) + μ 1 u ( 1 − u − a 1 v ) , v t = ∇ ⋅ ( ψ ( v ) ∇ v ) − χ 2 ∇ ⋅ ( v ∇ w ) + μ 2 v ( 1 − a 2 u − v ) , w t = Δ w − γ w + α u + β v , $$\textstyle\
Shuangshuang Zhou, Chunxiao Yang
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The Global Existence and Boundedness of Solutions to a Chemotaxis–Haptotaxis Model with Nonlinear Diffusion and Signal Production

open access: yesMathematics
In this paper, we investigate the following chemotaxis–haptotaxis system (1) with nonlinear diffusion and signal production under homogenous Neumann boundary conditions in a bounded domain with smooth boundary.
Beibei Ai, Zhe Jia
doaj   +1 more source

Uniform Boundedness Principle [PDF]

open access: yesFormalized Mathematics, 2008
Summary. In this article at first, we proved the lemma of the inferior limitand the superior limit. Next, we proved the Baire category theorem (Banach spaceversion) [20], [9], [3], quoted it and proved the uniform boundedness principle.Moreover, the proof of the Banach-Steinhaus theorem is added.MML identifier: LOPBAN 5, version: 7.8.05 4.89.993 The ...
Hideki Sakurai   +2 more
openaire   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Criteria for the asymptotic behaviour of solutions to certain third-order nonlinear differential equations [PDF]

open access: yesMathematica Moravica
We investigate and provide sufficient criteria for ultimate boundedness of solutions as well as the asymptotic stability of the trivial solution to certain nonlinear differential equation of order three. Using the Lyapunov second method and the Yoshizawa
Adeyanju A.A.   +7 more
doaj   +1 more source

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