Results 51 to 60 of about 18,338 (317)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Uniform Boundedness Principle [PDF]

open access: yesFormalized Mathematics, 2008
Summary. In this article at first, we proved the lemma of the inferior limitand the superior limit. Next, we proved the Baire category theorem (Banach spaceversion) [20], [9], [3], quoted it and proved the uniform boundedness principle.Moreover, the proof of the Banach-Steinhaus theorem is added.MML identifier: LOPBAN 5, version: 7.8.05 4.89.993 The ...
Hideki Sakurai   +2 more
openaire   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Multilinear analysis for discrete and periodic pseudo-differential operators in Lp-spaces

open access: yesRevista Integración, 2018
In this note we announce our investigation on the Lp properties for periodic and discrete multilinear pseudo-differential operators. First, we review the periodic analysis of multilinear pseudo-differential operators by showing classical multilinear ...
Duván Cardona, Vishvesh Kumar
doaj  

Boundedness of Vector Linéard Equation with Multiple Variable Delays

open access: yesMathematics
In this article, we consider a system of ordinary differential equations (ODEs) of second order with two variable time delays. We obtain new conditions for uniform ultimate bounded (UUB) solutions of the considered system.
Melek Gözen
doaj   +1 more source

A note on the boundedness in a chemotaxis-growth system with nonlinear sensitivity

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2018
This paper deals with a parabolic-elliptic chemotaxis-growth system with nonlinear sensitivity \begin{equation*}\label{1a} \begin{cases} u_t=\Delta u-\chi\nabla\cdot(\psi(u)\nabla v)+f(u), &(x,t)\in \Omega\times (0,\infty), \\ 0=\Delta v-v+g(u), &(x,t ...
Pan Zheng   +3 more
doaj   +1 more source

Amalgams and \(\chi\)-boundedness

open access: yesJ. Graph Theory, 2017
Summary: A class of graphs is hereditary if it is closed under isomorphism and induced subgraphs. A class \(\mathcal G\) of graphs is \(\chi\)-bounded if there exists a function \(f:\mathbb{N} \to \mathbb{N}\) such that for all graphs \(G\in \mathcal{G}\), and all induced subgraphs \(H\) of \(G\), we have that \(\chi(H)\leq f(\omega(H))\).
openaire   +1 more source

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