Results 111 to 120 of about 16,644 (310)

Spectral Bounds for Quasi-Twisted Codes

open access: yes, 2019
New lower bounds on the minimum distance of quasi-twisted codes over finite fields are proposed. They are based on spectral analysis and eigenvalues of polynomial matrices.
Ezerman, Martianus Frederic   +7 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

On the Griesmer bound for nonlinear codes

open access: yesCoRR, 2015
Most bounds on the size of codes hold for any code, whether linear or nonlinear. Notably, the Griesmer bound, holds only in the linear case. In this paper we characterize a family of systematic nonlinear codes for which the Griesmer bound holds. Moreover, we show that the Griesmer bound does not necessarily hold for a systematic code by showing ...
Emanuele Bellini 0002   +3 more
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Iterative Construction of Reversible Variable-Length Codes and Variable-Length Error-Correcting Codes

open access: yes, 2004
We propose a generic algorithm for the construction of efficient reversible variable-length codes (RVLCs) and variable-length error-correcting (VLEC) codes, which optimizes the codeword length distribution.
Wang, J., Yang, L-L., Hanzo, L.
core  

On 2-Repeated Burst Codes

open access: yesRatio Mathematica, 2009
There are several kinds of burst errors for which error detecting and error correcting codes have been constructed. In this paper, we consider a new kind of burst error which will be termed as ‘2-repeated burst error of length b(fixed)’.
B. K. Dass, Poonam Garg
doaj  

Bounds on Subspace Codes Based on Subspaces of Type (m,1) in Singular Linear Space

open access: yesJournal of Applied Mathematics, 2014
The Sphere-packing bound, Singleton bound, Wang-Xing-Safavi-Naini bound, Johnson bound, and Gilbert-Varshamov bound on the subspace codes n+l,M,d,(m,1)q based on subspaces of type (m,1) in singular linear space Fq(n+l) over finite fields Fq are presented.
You Gao, Gang Wang
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Closed-Form Approximation of Maximum Free Distance for Binary Block Codes

open access: yes, 2009
We devise an analytically simple as well as invertible approximate expression, which describes the relation between the maximum free distance of a binary code and the corresponding maximum attainable code-rate.
Akhtman, Jos   +7 more
core   +1 more source

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