Results 131 to 140 of about 713,380 (292)
An exact approach for single machine scheduling with quadratic earliness and tardiness penalties [PDF]
In this paper, we consider the single machine scheduling problem with quadratic earliness and tardiness costs, and no machine idle time. We propose two different lower bounds, as well as a lower bounding procedure that combines these two bounds.
Jorge M. S. Valente
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
The impact of climate factors on agricultural development: ARDL bounds test approach
Agricultural and Resource EconomicsPurpose. This study aims to examine the long-term and short-term impacts of climatic factors on agricultural development in the Nakhchivan Autonomous Republic, a semi-arid region of Azerbaijan.
Elnara Seyidova +2 more
doaj +1 more source
A Panel Bounds Testing Procedure
SSRN Electronic Journal, 2022 Georgios Bertsatos +2 more
openaire +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Efficient Tests of the Seasonal Unit Root Hypothesis* [PDF]
In this paper we derive, under the assumption of Gaussian errors with known error covariance matrix, asymptotic local power bounds for seasonal unit root tests for both known and unknown deterministic scenarios and for an arbitrary seasonal aspect.
A.M. Robert Taylor, Paulo M.M. Rodrigues
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Is There A Long-Run Relationship Between Taxation And Growth: The Case Of Turkey [PDF]
This paper empirically investigates long-run equilibrium relationship between economic growth and tax revenues in Turkey by using the bounds test and Johansen technique for cointegration.
Katircioglu, Salih Turan
core
Testing $C_k$-freeness in bounded-arboricity graphs
We study the problem of testing $C_k$-freeness ($k$-cycle-freeness) for fixed constant $k > 3$ in graphs with bounded arboricity (but unbounded degrees). In particular, we are interested in one-sided error algorithms, so that they must detect a copy of $C_k$ with high constant probability when the graph is $ε$-far from $C_k$-free.
Eden, Talya, Levi, Reut, Ron, Dana
openaire +4 more sources