Results 51 to 60 of about 16,238 (186)

The Arrival of Exome Sequencing in French Prenatal Diagnosis: An Exploratory Qualitative Study Among Professionals in Prenatal Diagnosis Centers: Prenatome‐SHS

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Following the first French multicenter pilot study (AnDDI‐Prenatome) focused on the implementation of prenatal exome sequencing (pES), this ancillary study aims to explore the ethical and clinical issues raised by pES within multidisciplinary prenatal diagnosis centers.
Charlène Daval, Nicolas Meunier‐Beillard, Eléonore Viora‐Dupont, Julian Delanne, Aurore Garde, Caroline Racine, Frédéric Tran Mau‐Them, Anne‐Sophie Denommé‐Pichon, Christophe Philippe, Ange‐Line Bruel, Hana Safraou, Sylvie Odent, Chloé Quélin, Marine Legendre, Sophie Naudion, Médéric Jeanne, Marie‐Line Jacquemont, Agnès Guichet, Camille Saldana, Anne‐Marie Guerrot, Alice Goldenberg, Caroline Guégan, Marie Vincent, Audrey Putoux, Christine Francannet, Constance Wells, Chloé Arthuis, Elodie Alexandre, Thierry Rousseau, Olivia Martz, Emilie Simon, Ornella Magnien, Fanny Bobert, Sophie Bert, Frédéric Coatleven, Fanny Reveyaz, Perrine Moulinié, Christine Binquet, Christel Thauvin‐Robinet, Laurence Faivre   +39 more
wiley   +1 more source

Impact of ticagrelor on P2Y1 and P2Y12 localization and on cholesterol levels in platelet plasma membrane

Platelets, 2018
Ticagrelor is an antiplatelet agent that inhibits platelet activation via P2Y12 antagonism. There are several studies showing that P2Y12 needs lipid rafts to be activated, but there are few data about how ticagrelor impacts lipid raft organization ...
Vahideh Rabani, Damien Montange, Nicolas Meneveau, Siamak Davani   +3 more
doaj   +1 more source

Factors Produced by Macrophages Eliminating Apoptotic Cells Demonstrate Pro-Resolutive Properties and Terminate Ongoing Inflammation

Frontiers in Immunology, 2018
Unresolved inflammation is a common feature in the pathogenesis of chronic inflammatory/autoimmune diseases. The factors produced by macrophages eliminating apoptotic cells during resolution are crucial to terminate inflammation, and for subsequent ...
Francis Bonnefoy, Thierry Gauthier, Romain Vallion, Omayra Martin-Rodriguez, Anais Missey, Anna Daoui, Séverine Valmary-Degano, Philippe Saas, Mélanie Couturier, Mélanie Couturier, Sylvain Perruche, Sylvain Perruche   +11 more
doaj   +1 more source

Agroecology and Transformative Adaptation to Climate Change

Asia Pacific Viewpoint, EarlyView.
ABSTRACT This paper examines transformative adaptation to climate change through the EFICAS Project (Eco‐Friendly Intensification and Climate‐resilient Agricultural Systems) implemented across 12 upland communities in northern Laos from 2014 to 2020.
Jean‐Christophe Castella
wiley   +1 more source

Recent insights into the implications of metabolism in plasmacytoid dendritic cell innate functions: Potential ways to control these functions [version 1; referees: 1 approved, 2 approved with reservations]

F1000Research, 2017
There are more and more data concerning the role of cellular metabolism in innate immune cells, such as macrophages or conventional dendritic cells. However, few data are available currently concerning plasmacytoid dendritic cells (PDC), another type of ...
Philippe Saas, Alexis Varin, Sylvain Perruche, Adam Ceroi   +3 more
doaj   +1 more source

Élaboration d’un observatoire climatique dans la Réserve Naturelle Régionale et Forêts d’Exception du Val Suzon (Bourgogne-Franche-Comté, France)

Climatologie
Le changement climatique remet en question les stratégies de gestion des milieux naturels. Dans la Réserve Naturelle Régionale et Forêts d’Exception du Val Suzon (RNR-FE), la richesse de la biodiversité tient en partie au climat spécifique de la vallée ...
Guillaume Huteau, Sarah Prunot, Thomas Marchal, Marlène Tréca, Mario Rega, Pascal Roucou, Y. Richard   +6 more
semanticscholar   +1 more source

Anticipating tomorrow: The role of corporate foresight and prospective sensemaking in managing digital changes by established organizations

European Management Review, EarlyView.
Abstract In the digital era, established organizations face significant challenges in adapting to unfolding changes. This study explores the reciprocal relationship between prospective sensemaking and corporate foresight within a large European bank engaged in digital transformation through its corporate accelerator program.
Anna‐Sofia Yanson, Mohamad Najib Tarhini, Daniele Cerrato   +2 more
wiley   +1 more source

Potential added value of a RT-qPCR method of SOX 11 expression, in the context of a multidisciplinary diagnostic assessment of B cell malignancies

Experimental Hematology & Oncology, 2018
Background Expression of SRY [sex-determining region Y]-box11 (SOX11) is specific to mantle cell lymphoma (MCL) and contributes, in conjunction with immunoglobulin variable heavy chain gene mutation status, to the identification of two forms of this ...
Julien Magne, Alizée Jenvrin, Adrien Chauchet, Olivier Casasnovas, Anne Donzel, Laurence Jego, Bernard Aral, Julien Guy, Nathalie Nadal, Dewi Vernerey, Patrick Callier, Francine Garnache-Ottou, Christophe Ferrand   +12 more
doaj   +1 more source

Field‐based evidence of impaired sperm quality associated with conventional farming in two passerine birds

Ibis, EarlyView.
The detrimental effects of conventional farming on bird biodiversity are increasingly documented. Despite this, the specific impacts of both organic and conventional farming practices on bird coloration and sperm quality in natural settings remain unexplored. This study aimed to determine whether these farming practices differentially affect body mass,
Ségolène Humann‐Guilleminot, Audrey Bailly, Karine Monceau, Mélissa Desbonnes, Vincent Bretagnolle, Jérôme Moreau   +5 more
wiley   +1 more source

Bortezomib as a new therapeutic approach for blastic plasmacytoid dendritic cell neoplasm

Haematologica, 2017
Blastic plasmacytoid dendritic cell neoplasm is an aggressive hematologic malignancy with a poor prognosis. No consensus regarding optimal treatment modalities is currently available. Targeting the nuclear factor-kappa B pathway is considered a promising
Laure Philippe, Adam Ceroi, Elodie Bôle-Richard, Alizée Jenvrin, Sabeha Biichle, Sophie Perrin, Samuel Limat, Francis Bonnefoy, Eric Deconinck, Philippe Saas, Francine Garnache-Ottou, Fanny Angelot-Delettre   +11 more
doaj   +1 more source