Results 181 to 190 of about 188,135 (200)
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A vhs-like activity of bovine herpesvirus-1
Archives of Virology, 2000Bovine herpesvirus 1 (BHV-1) is a major pathogen of cattle, causing significant disease including immunosuppression in infected animals. In vitro, the surface expression of major histocompatibility complex (MHC) class I molecules, crucial for an appropriate anti-viral immune response of the host, is down-regulated by BHV-1 infection.
S, Hinkley +3 more
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American Journal of Veterinary Research, 1982
SUMMARY The onset of protection offered by intranasal vaccination with attenuated bovine herpesvirus-1 (bhv-1) was studied in 18 calves given a virulent bhv-1 aerosol challenge inoculum and an aerosol challenge exposure to Pasteurella haemolytica. Calves challenge exposed with virus 3, 7, 11, 15, or 19 days after vaccination and challenge exposed 4 ...
K W, Jericho, W D, Yates, L A, Babiuk
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SUMMARY The onset of protection offered by intranasal vaccination with attenuated bovine herpesvirus-1 (bhv-1) was studied in 18 calves given a virulent bhv-1 aerosol challenge inoculum and an aerosol challenge exposure to Pasteurella haemolytica. Calves challenge exposed with virus 3, 7, 11, 15, or 19 days after vaccination and challenge exposed 4 ...
K W, Jericho, W D, Yates, L A, Babiuk
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Research in Veterinary Science, 1991
The protective effect of an inactivated whole-virion bovine herpesvirus-1 (BHV-1) immunising inoculum, without adjuvant, against viral-bacterial respiratory disease was studied in three experimental treatment groups of five calves each. One group was boosted 14 days after the first vaccination and at this time the second group received their initial ...
K W, Jericho +3 more
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The protective effect of an inactivated whole-virion bovine herpesvirus-1 (BHV-1) immunising inoculum, without adjuvant, against viral-bacterial respiratory disease was studied in three experimental treatment groups of five calves each. One group was boosted 14 days after the first vaccination and at this time the second group received their initial ...
K W, Jericho +3 more
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Analysis of bovine trigeminal ganglia following infection with bovine herpesvirus 1
Veterinary Microbiology, 2002Following primary infection of the eye, oral cavity, and/or nasal cavity, bovine herpesvirus 1 (BHV-1) establishes latency in trigeminal ganglionic (TG) neurons. Virus reactivation and spread to other susceptible animals occur after natural or corticosteroid-induced stress.
M T C, Winkler +3 more
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Modified Bovine Herpesvirus 1 for Protein Secretion
2009The traditional way to utilize bovine herpesvirus 1 (BHV-1) and many other herpesviruses as vectors for synthesis of heterologous proteins like reporter proteins, antigens, or immunomodulatory active molecules was (and still is) the expression of the protein of interest from an entire gene consisting of promoter, 5'- and 3'-noncoding regions, the open ...
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Archives of Virology, 2010
The aim of this study was to analyze the disordered regions (DRs) in the envelope and tegument proteins of three closely related herpesviruses: bovine herpesvirus 1, bovine herpesvirus 5 and suid herpesvirus 1. Tegument proteins showed a greater percentage of DRs than the envelope proteins did.
A A, Fonseca +3 more
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The aim of this study was to analyze the disordered regions (DRs) in the envelope and tegument proteins of three closely related herpesviruses: bovine herpesvirus 1, bovine herpesvirus 5 and suid herpesvirus 1. Tegument proteins showed a greater percentage of DRs than the envelope proteins did.
A A, Fonseca +3 more
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Vaccine, 1988
It has been reported previously that active bovine herpesvirus-1 (BHV-1) infection greatly enhances the susceptibility of cattle to secondary bacterial pneumonia involving Pasteurella haemolytica. The present study examines the possibility that immunization of BHV-1 naive calves with purified BHV-1 glycoproteins would protect them against changes in ...
E J, Noel +3 more
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It has been reported previously that active bovine herpesvirus-1 (BHV-1) infection greatly enhances the susceptibility of cattle to secondary bacterial pneumonia involving Pasteurella haemolytica. The present study examines the possibility that immunization of BHV-1 naive calves with purified BHV-1 glycoproteins would protect them against changes in ...
E J, Noel +3 more
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Bovine Herpesvirus 1 Downregulates the Expression of Bovine MHC Class I Molecules
Viral Immunology, 1997The mechanism of immunosuppression induced by bovine herpesvirus 1 (BHV-1) was investigated by studying the effects of the virus on the expression of major histocompatibility complex (MHC) class I molecules. After infection with the virus, the expression of class I molecules was detected by flow cytometry and pulse-chase analysis.
C, Nataraj +5 more
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Bovine herpesvirus-1 infection affects the peptide transport activity in bovine cells
Virus Research, 1998Infection of cattle with bovine herpesvirus-1 (BHV-1) impairs the cell-mediated immune response (CMI) of the affected host. We investigated the location of interference of BHV-1 with the major histocompatibility complex (MHC) class I antigen presentation pathway by employing an assay that allows assessment of the peptide transport activity of the ...
S, Hinkley, A B, Hill, S, Srikumaran
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Patterns of bovine T cell-mediated immune responses to bovine herpesvirus 1
Veterinary Immunology and Immunopathology, 1986Lymphocyte proliferation was used to evaluate T cell-mediated immune responses to different isolates of Bovine Herpesvirus 1 (BHV-1). Groups of high, moderate, and low responses were observed when lymphocytes from three breeds of dairy cattle were stimulated with each of the BHV-1 isolates.
M, Miller-Edge, G, Splitter
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