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Vaccination Trials Against Bovine Herpesvirus-1

Veterinary Research Communications, 2005
G. Castrucci1,∗, M. Ferrari2, D. Salvatori3, S. Sardonini4, F. Frigeri5, S. Petrini1, M. Lo Dico1, C. Marchini6, A. Rotola7, A. Amici6, M. Provinciali8, A. Tosini2, R. Angelini4 and E. Cassai7 1University of Perugina; 2Zooprophylaxis Institute, Brescia; 3Royal Veterinary College, London, UK; 4A.S.L.
CASTRUCCI G   +13 more
openaire   +4 more sources

Immunology of bovine herpesvirus 1 infection

Veterinary Microbiology, 1996
Immune responses to bovine herpesvirus 1 (BHV-1) have been studied following exposure of animals to virulent virus, conventional live or killed vaccines, genetically engineered live virus vaccines, subunit vaccines and, more recently, following immunization with plasmids encoding putative protective antigens.
L A, Babiuk   +2 more
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Infection of early bovine embryos with bovine herpesvirus-1

American Journal of Veterinary Research, 1985
SUMMARY Recently hatched bovine embryos were exposed in vitro to 1 of 4 strains of bovine herpesvirus-1 to determine whether the viruses would replicate in these embryos and, if so, what pathologic consequences would ensue. Exposure to each of the viruses resulted in embryonic infection and death, and replication of the agents was demonstrated by ...
R A, Bowen, R P, Elsden, G E, Seidel
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Recombination in the alphaherpesvirus bovine herpesvirus 1

Veterinary Microbiology, 2006
Herpesviruses are DNA viruses characterized by a low rate of nucleotide substitution. Therefore, other mechanisms must be involved to their evolution, like recombination that can be seen as an essential evolutionary driving force of these viruses. Recombination contributes to the long-term evolution of alphaherpesviruses.
Thiry, Etienne   +6 more
openaire   +3 more sources

Bovine monoclonal antibodies specific for bovine herpesvirus-1 glycoprotein gIII

American Journal of Veterinary Research, 1990
SUMMARY Spleen cells from a calf immunized with bovine herpesvirus-1 (BHV-1) were fused with the nonsecreting murine cell line SP2/0. Several bovine-murine hybridomas secreting bovine immunoglobulins were stabilized. Of these, 9 hybridomas secreted bovine monoclonal antibodies that specifically bound to BHV-1 in a radioimmunoassay.
S, Srikumaran   +4 more
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Temporal control of bovine herpesvirus 1 glycoprotein synthesis

Journal of Virology, 1987
The gI, gIII, and gIV glycoproteins are major bovine herpesvirus 1 antigens involved in virus neutralization. Results indicate that the gI and gIV glycoproteins were expressed as beta proteins, whereas the gIII glycoprotein was expressed strictly as a gamma protein. These findings suggest that gI and gIV may be superior to gIII as vaccine candidates.
G V, Ludwig, G J, Letchworth
openaire   +2 more sources

Characteristics of live bovine herpesvirus-1 vaccines

The Veterinary Journal, 2005
The common disease caused by bovine herpes virus 1 infection is febrile rhinotracheitis (FRT) and under certain conditions the virus is strongly implicated in pre-disposing cattle to pneumonic pasteurellosis. These illnesses account for a significant economic loss in the cattle industry worldwide and vaccination is widely applied.
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A vhs-like activity of bovine herpesvirus-1

Archives of Virology, 2000
Bovine herpesvirus 1 (BHV-1) is a major pathogen of cattle, causing significant disease including immunosuppression in infected animals. In vitro, the surface expression of major histocompatibility complex (MHC) class I molecules, crucial for an appropriate anti-viral immune response of the host, is down-regulated by BHV-1 infection.
S, Hinkley   +3 more
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Bovine herpesvirus-1 vaccination against experimental bovine herpesvirus-1 and Pasteurella haemolytica respiratory tract infection: Onset of protection

American Journal of Veterinary Research, 1982
SUMMARY The onset of protection offered by intranasal vaccination with attenuated bovine herpesvirus-1 (bhv-1) was studied in 18 calves given a virulent bhv-1 aerosol challenge inoculum and an aerosol challenge exposure to Pasteurella haemolytica. Calves challenge exposed with virus 3, 7, 11, 15, or 19 days after vaccination and challenge exposed 4 ...
K W, Jericho, W D, Yates, L A, Babiuk
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Protective effect of inactivated bovine herpesvirus-1 in calves experimentally infected with bovine herpesvirus-1 and Pasteurella haemolytica

Research in Veterinary Science, 1991
The protective effect of an inactivated whole-virion bovine herpesvirus-1 (BHV-1) immunising inoculum, without adjuvant, against viral-bacterial respiratory disease was studied in three experimental treatment groups of five calves each. One group was boosted 14 days after the first vaccination and at this time the second group received their initial ...
K W, Jericho   +3 more
openaire   +2 more sources

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