Results 121 to 130 of about 103,996 (284)

The viral origins of breast cancer

open access: yesInfectious Agents and Cancer
During the past two decades evidence has been developed that indicates a handful of viruses with known oncogenic capacity, have potential roles in breast cancer.
James S. Lawson, Wendy K. Glenn
doaj   +1 more source

Endoplasmic Reticulum Stress Amplifies Cytokine Responses in Astrocytes via a PERK/eIF2α/JAK1 Signaling Axis

open access: yesGlia, EarlyView.
ER stress amplifies TNF‐α, OSM, and IL‐1β responses in astrocytes. PERK and JAK1 signaling are required for the synergistic interaction between ER stress and inflammatory cytokines. Translational suppression attenuates the synthesis of the negative feedback regulators IκBα and SOCS3.
Anirudhya Lahiri   +8 more
wiley   +1 more source

Detection of specific antibodies of classes G and M to bovine leukemia virus in the blood serum

open access: yesВопросы вирусологии, 2019
Introduction. Bovine leukemia is a widespread infection worldwide, the causative agent of which is the bovine leukemia virus (BLV) in structural structure and functional features similar to human T-cell leukemia virus (HTLV-1 and HTLV-2) and It is ...
M. I. Gulyukin   +5 more
doaj   +1 more source

Dysregulation of Monounsaturated Fatty Acids is Related to α‐Synuclein in Multiple System Atrophy

open access: yesMovement Disorders, EarlyView.
Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease pathologically characterized by the presence of glial cytoplasmic inclusions (GCI) composed of α‐synuclein aggregates. In Parkinson's disease, increases in monounsaturated fatty acids (MUFA) in phospholipid membranes promote α‐synuclein binding, aggregation, and toxicity ...
Finula I. Isik   +8 more
wiley   +1 more source

CAT1/SLC7A1 acts as a cellular receptor for bovine leukemia virus infection

open access: yesbioRxiv, 2019
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, the most common neoplastic disease of cattle, which is closely related to human T-cell leukemia viruses.
Lanlan Bai   +4 more
semanticscholar   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

Spontaneous virus reactivation in cattle chronically infected with bovine leukemia virus

open access: yesBMC Veterinary Research, 2019
Background The absence of virus expression during the chronic stage of bovine leukemia virus (BLV) infection and its reactivation upon ex vivo culture has become a long-lived Dogma.
Juan Pablo Jaworski   +3 more
doaj   +1 more source

Near‐Infrared‐Triggered Nanodroplets for Imaging‐Guided Macrophage‐Mediated Cancer Immunotherapy

open access: yesSmall Methods, EarlyView.
Schematic illustration of the Nanodroplets and their theranostics application–The engineered nanodroplets integrate a multifunctional design, encapsulating the immunostimulant resiquimod (R848), indocyanine green (ICG), and volatile perfluoropentane (PFP), within a biocompatible double‐emulsion structure.
Junxi Yi   +3 more
wiley   +1 more source

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