Results 141 to 150 of about 103,996 (284)

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

open access: yesBrain Pathology, EarlyView.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie   +9 more
wiley   +1 more source

SHBs Mitigates Sorafenib‐Induced Apoptosis in Hepatocellular Carcinoma via Activation of RAF1/MEK/ERK Signaling Pathway

open access: yesCancer Science, EarlyView.
Hepatitis B virus (HBV) infection is a major driver of hepatocellular carcinoma (HCC) and is associated with resistance to sorafenib, the first‐line treatment for advanced HCC. This study demonstrates that the small HBV surface antigen (SHBs) promotes sorafenib resistance by activating the RAF1/MEK/ERK signaling pathway, inhibiting apoptosis in HCC ...
Shuxiang Wu   +6 more
wiley   +1 more source

A comparative study for diagnosis of Bovine Leukemia Virus (BLV) infection in dairy cows by Polymerase Chain Reaction (PCR) and Enzyme Linked Immunosorbent assay (ELISA) [PDF]

open access: yesĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2015
Bovine Leukemia Virus (BLV) is a retrovirus that causes bovine enzootic leukemia (EBL). The routine method for the diagnosis of the infection is antibody screening tests.
raziallah jafari jozani   +2 more
doaj  

Different bovine leukemia virus-induced tumors harbor the provirus in different chromosomes [PDF]

open access: bronze, 1984
D. Grégoire   +9 more
openalex   +1 more source

Radiographic Peri‐Implant Bone Changes in Osteoporotic Women Treated With a Ti‐Zr, Bone Level Tapered Implant With a Hydrophilic Surface: A 12‐Month Prospective Case‐Series

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This study assessed 12‐month post‐loading 3D peri‐implant radiographic bone changes in osteoporotic women receiving a single titanium‐zirconium bone‐level tapered dental implant with a hydrophilic surface. Materials and Methods This was a prospective case series involving 18 post‐menopausal osteoporotic women in need of a single ...
Calciolari Elena   +4 more
wiley   +1 more source

Bovine Leukemia Virus

open access: yesVIRUS Reviews & Research, 2004
Marcelo Fernandes Camargos   +2 more
openaire   +2 more sources

Advances in the Study of Pluripotent Stem Cells in Livestock

open access: yesCell Proliferation, EarlyView.
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou   +6 more
wiley   +1 more source

Targeting SHP‐1‐Mediated Inhibition of STAT3 and ERK Signalling Pathways Rescues the Hyporesponsiveness of MHC‐I‐Deficient NK‐92MI

open access: yesCell Proliferation, EarlyView.
B2M knockout (KO) represents a crucial strategy for generating universal NK‐92MI cell products. This approach results in increased phosphorylation of SHP‐1 and inhibited phosphorylation of STAT3 and ERK, which ultimately affect their cytotoxic capabilities. SHP‐1 KO facilitates the restoration of cytotoxic function in B2M KO NK‐92MI cells.
Kuo Yu   +17 more
wiley   +1 more source

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