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Tandemization Endows Bovine Pancreatic Ribonuclease with Cytotoxic Activity

Journal of Molecular Biology, 2006
Due to their ability to degrade RNA, selected members of the bovine pancreatic ribonuclease A (RNase A) superfamily are potent cytotoxins. These cytotoxic ribonucleases enter the cytosol of target cells, where they degrade cellular RNA and cause cell death.
Jens Köditz   +3 more
openaire   +3 more sources

Production of mature bovine pancreatic ribonuclease in Escherichia coli

Gene, 1992
The coding sequence for the bovine pancreatic ribonuclease (RNase) precursor has been cloned and produced in Escherichia coli using the polymerase chain reaction (PCR) technique. A PCR amplification has been carried out utilizing as template the recombinant plasmid, pQR138, which contains the coding sequence for the RNase precursor, and primers that ...
Christopher John Taylorson   +3 more
openaire   +3 more sources

Molecular aggregation of bovine pancreatic ribonuclease induced by substrate

Archives of Biochemistry and Biophysics, 1970
Abstract The interaction between bovine cytidine-2′,3′-cyclic phosphate pancreatic ribonuclease and ribonucleic acid or cytidine-2′,3′-cyclic phosphate is studied by means of the gel-filtration method. The formation of a molecular aggregate of the enzyme as a function of time is shown.
L. Galzigna, A. Marzotto
openaire   +3 more sources

Proteopedia entry: Bovine pancreatic ribonuclease a [PDF]

open access: possibleBiochemistry and Molecular Biology Education, 2011
Elizabeth E. Ellis   +19 more
openaire   +1 more source

The conformation of bovine pancreatic ribonuclease S-peptide

Chemical Communications (London), 1967
E. Scoffone   +3 more
openaire   +2 more sources

The reaction of 9-azidoacridine with bovine pancreatic ribonuclease [PDF]

open access: possibleBiochemical Society Transactions, 1982
Surendra Pal Batra, Bruce H. Nicholson
openaire   +1 more source

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