Results 201 to 210 of about 172,440 (283)
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos +12 more
wiley +1 more source
Frequency of Bovine Respiratory Disease Complex Bacterial and Viral Agents Using Multiplex Real-Time qPCR in Quebec, Canada, from 2019 to 2023. [PDF]
Buczinski S, Broes A, Savard C.
europepmc +1 more source
Dembo polymerase chain reaction technique for detection of bovine abortion, diarrhea, and respiratory disease complex infectious agents in potential vectors and reservoirs [PDF]
Sayed Samim Rahpaya +25 more
openalex +1 more source
Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini +24 more
wiley +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab +16 more
wiley +1 more source
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan +10 more
wiley +1 more source
Validation of a clinical scoring system for bovine respiratory disease complex diagnosis in preweaned dairy calves using a Bayesian framework. [PDF]
Buczinski S +3 more
europepmc +1 more source

