Results 61 to 70 of about 10,476,926 (247)

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

ANTIGENIC AND MOLECULAR IDENTIFICATION OF SOME VIRUSES CAUSING RESPIRATORY DISORDER IN CALVES

Assiut Veterinary Medical Journal, 2009
  Bovine parainfluenza virus Type 3 (BPI3) and bovine respiratory syncytial virus (BRSV), are ubiquitous respiratory pathogens of cattle, which contribute to causation of bovine respiratory disease complex.
HANAA A.M. GHONIEM, NAHED A. MAHMOUD, OMAYMA A. SHEMIES, JEHAN A. GAFER   +3 more
doaj   +1 more source

New Techniques to Evaluate Functional Impact of Bovine Respiratory Disease

, 1998
Despite prophylactic measures, mainly including vaccination programs and management measures, respiratory disease remains the major cause of economic losses in bovine species.
Uystepruyest, Ch, Coghe, J., Bureau, F., Van der Weerdt, M. L., Lekeux, P.   +4 more
core   +1 more source

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source

Comparative Efficacy of Tulathromycin and Ceftiofur for Treating Undifferentiated BRDC and Tulathromycin Metaphylaxis in Dairy Cattle

Antibiotics
Background/Objectives: Bovine respiratory disease complex (BRDC) is commonly treated empirically, as etiological diagnosis is often impractical under field conditions.
Sahaphop Pengpanun, Surachet Panyapan, Tawatchai Singhla   +2 more
doaj   +1 more source

Modern Approach to the Enigma of Bovine Respiratory Disease Complex: A Review [PDF]

Pakistan Veterinary Journal, 2014
Research on Bovine Respiratory Disease Complex (BRDC) has strongly contributed to a better understanding of disease at both global and local levels. New agents have been identified and their nature has been better known since then, as well as all the ...
Vladimir S. Kurćubić, Radojica D. Đoković, Zoran Ž. Ilić, Jovan S. Stojković, Milan P. Petrović, Violeta Caro-Petrović   +5 more
doaj  

Current Observations On The Bovine Respiratory Disease Complex In High Plains Feedyards

, 1979
The bovine respiratory disease (BRO) complex is more complex than an elephant. Just as the blind men gave diverse descriptions of the elephant, comments concerning BRO will certainly vary according to the bias of the observer. The following biased report
Brown, L. N.
core   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Diagnostic Considerations for Bovine Respiratory Disease

, 1996
Bovine respiratory disease remains a significant cause of economic loss to the cattle industry1 and source of frustration to the cow/calf sector, the feedlot industry, veterinary practitioners and laboratory diagnosticians.
Kennedy, George A.
core   +1 more source