Results 151 to 160 of about 881,797 (260)

Aβ1‐40 induces venular endothelial cell ferroptosis in cerebral amyloid angiopathy via the ATF3/xCT axis: Insights from single‐cell RNA sequencing

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Amyloid‐beta (Aβ)‐induced microvascular injury is a key pathological feature of cerebral amyloid angiopathy (CAA). Recent evidence suggests that ferroptosis is implicated in Aβ pathology; however, its cell‐type specificity and regulatory mechanisms within the cerebral microvasculature in CAA remain unclear. METHODS Single‐cell RNA
Chunmei Wu, Xiaodong Ye, Hualin Chen, Yongkang Fang, Yan Lan, Jiahe Ye, Xin Liu, Ruizhi Xiao, Suiqiang Zhu, Shanshan Huang   +9 more
wiley   +1 more source

Harnessing microbial metabolism and nutrition to target the gut–mammary axis for better livestock production and health

iMetaOmics, Volume 3, Issue 3, September 2026.
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou, Cheng Guo, Mahmoud M. Abdelsattar, Ahmad R. Musa, Mequanint Biks, Abdullahi A. Musa, Shahnaz Rahman, Abera Teshome Aleli, Pei Zhong, Jiawei Zhang, Junwei Cui, Xiyan Kou, Qingyuan Yu, Caijuan Yue, Qin Li, Dan Zhang, Zixuan Peng, Ao Ren, Ziqi Tian, Ziqi Liu, Yaona Zhang, Lili Zhang, Dina Karmallah, Naifeng Zhang, Tao Ma, Yan Tu, Qiyu Diao, Guijie Zhang, Xiaofeng Xu, Yanliang Bi   +29 more
wiley   +1 more source

Outbreaks of pneumonia in beef calves associated with bovine viral diarrhea virus seroconversion and other respiratory pathogens

Journal of Veterinary Medical Research, 2005
The present study describes the clinical, serological and bacteriolological findings in calves from two beef herds experiencing outbreaks of pneumonia. The clinical signs were nasal discharge, cough, pyrexia and increased respiratory rates.
A. M. Khadr
doaj  

Dysregulation of the KLF9/TXNRD2 Axis Leads to Mitochondrial DNA Oxidation and NLRP3 Inflammasome Activation in Ulcerative Colitis

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
In ulcerative colitis, the transcription factor KLF9 is abnormally overexpressed and inhibits TXNRD2 transcription. As a key mitochondrial antioxidant enzyme, the loss of TXNRD2 leads to disruption of mitochondrial redox homeostasis, resulting in excessive accumulation of mtROS and mitochondrial DNA damage.
Yijia Fan, Lingling Dai, Feng Zhu, Mingfang Ping, Xiaofeng Zhu, Junguo Chen   +5 more
wiley   +1 more source

Genotypes of Bovine Viral Diarrhea Virus Infecting Vaccinated and Nonvaccinated Cattle in Thrace District, Türkiye. [PDF]

Viruses
Karadag G, Tali HE, Ozkan IE, Turan N, Umar S, Richt JA, Yilmaz H, Yilmaz A.   +7 more
europepmc   +1 more source

Neuronal Apoptotic Bodies Facilitate Japanese Encephalitis Virus Infection and Pathogenicity

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Japanese encephalitis (JE) caused by Japanese encephalitis virus (JEV) infection remains one of the major types of viral encephalitis. The mechanisms underlying JEV infection and pathogenesis have not been fully elucidated, resulting in the absence of specific therapies for JE. Neuronal apoptosis is a well‐established outcome of JEV infection;
Chuan Zeng, Xiaowei Nan, Ting Wang, Junyao Xiong, Shuo Zhu, Chengjie Yang, Bibo Zhu, Youhui Si, Shengbo Cao, Jing Ye   +9 more
wiley   +1 more source

Bovine viral diarrhea virus (BVDV) relies on cellular lipid droplet biogenesis and lipolysis to provide energy for viral replication. [PDF]

Vet Res
Xiong X, Liu Y, Zhu Y, Wang J, Yang G.
europepmc   +1 more source

Key Molecular Parameters of PEI for Efficient DNA Delivery Into HEK293T Cells

Macromolecular Chemistry and Physics, Volume 227, Issue 18, 29 September 2026.
Graphical representation of the formation and organization of PEI/eGPF‐C3 polyplexes and their relationship with intracellular plasmid accumulation and transfection efficiency in HEK293T cells. The data suggest that the hierarchical organization of b‐PEI25 polyplexes may contribute to enhanced intracellular plasmid accumulation and gene expression ...
Paulina Alejandra Montaño González, Manon Rochedy, Christophe Schatz, Jean‐Paul Chapel, Ma. Lizbeth Zepeda García, Alberto Gutiérrez Becerra, Sylvain Tranchimand, Patricia Leroyer, Fabienne Gauffre, Soizic Chevance, Pascal Loyer, Lourdes Mónica Bravo Anaya   +11 more
wiley   +1 more source

Genetic Evolutionary Analysis and Characterization of Bovine Viral Diarrhea Virus in Gansu Province, China. [PDF]

Viruses
Li C, Gao S, Mo Y, Liu Z, Zhou G, Cao X, He J, Yuan L, Shang Y.   +8 more
europepmc   +1 more source

Development of a Gold Nanoparticle‐Assisted Multiplex Polymerase Chain Reaction Assay for Selected Hospital‐Acquired Infections‐Associated Bacterial and Fungal Pathogens

ChemistryOpen, Volume 15, Issue 9, September 2026.
Gold nanoparticle‐assisted multiplex PCR enables the simultaneous detection of six major hospital‐acquired infection‐associated pathogens by improving amplification performance and assay specificity, providing an analytical proof‐of‐concept for rapid molecular identification.
Kubra Aslan, Emre Erden Kopar, Serap Evran   +2 more
wiley   +1 more source