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Molecular biology of bovine viral diarrhea virus
Biologicals, 2013Bovine viral diarrhea viruses (BVDV) are arguably the most important viral pathogen of ruminants worldwide and can cause severe economic loss. Clinical symptoms of the disease caused by BVDV range from subclinical to severe acute hemorrhagic syndrome, with the severity of disease being strain dependent.
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American Journal of Veterinary Research, 1985
SUMMARY Nine steers persistently infected with noncytopathic bovine viral diarrhea (bvd) virus were allotted into 3 groups (3 cattle/group). Cattle in group A were vaccinated with a modified-live bvd virus vaccine of porcine cell origin, cattle in group B with a modified-live bvd virus vaccine of bovine cell origin, and cattle in group C with a killed ...
S R, Bolin +3 more
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SUMMARY Nine steers persistently infected with noncytopathic bovine viral diarrhea (bvd) virus were allotted into 3 groups (3 cattle/group). Cattle in group A were vaccinated with a modified-live bvd virus vaccine of porcine cell origin, cattle in group B with a modified-live bvd virus vaccine of bovine cell origin, and cattle in group C with a killed ...
S R, Bolin +3 more
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Diagnosis of Bovine Viral Diarrhea Virus Infections
Veterinary Clinics of North America: Food Animal Practice, 1995Because of complex pathogenesis and insidious nature of BVDV infections, the laboratory diagnosis is an essential component of developing measures for the control and prevention of BVDV infections. The positive isolation of BVDV from animal submissions or from aborted fetuses should provide a strong indication for further epidemiologic investigations ...
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Veterinary Microbiology, 1997
The National Animal Disease Laboratory (NADL) vaccine strain of bovine viral diarrhea virus (BVDV) genes for gp48 and p80 were expressed in Escherichia coli. The BVDV-NADL gene for gp62 was integrated into a baculovirus genome for expression in Spodoptera frugiperda (Sf-9) insect ovarian cells. The antigenicity of baculovirus expressed BVDV protein was
Ogi Okwumabua +7 more
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The National Animal Disease Laboratory (NADL) vaccine strain of bovine viral diarrhea virus (BVDV) genes for gp48 and p80 were expressed in Escherichia coli. The BVDV-NADL gene for gp62 was integrated into a baculovirus genome for expression in Spodoptera frugiperda (Sf-9) insect ovarian cells. The antigenicity of baculovirus expressed BVDV protein was
Ogi Okwumabua +7 more
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Evolution of bovine viral diarrhea virus vaccines
Veterinary Clinics of North America: Food Animal Practice, 2004Control of bovine viral diarrhea virus (BVDV) infection is economically important to the cattle industry because the virus causes a variety of clinical diseases that adversely affect essentially all stages of the production cycle. Production losses primarily stem from reproductive failure and from immunosuppression during acute BVDV infection, which ...
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Bovine viral diarrhea virus proteins and their antigenic analyses [PDF]
, 1991 Bovine Viral Diarrhea Virus (BVDV) polypeptides present in infected cells are the result of the processing of the polyprotein translated from the large single open reading frame of the BVDV genomic RNA. The presence of these proteins in infected cells was studied by radiolabeling under hypertonic conditions and with the aid of radioimmunoprecipitation.
Edward J. Dubovi +2 more
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Vaccination of cattle against bovine viral diarrhea virus
Veterinary Microbiology, 2017Bovine viral diarrhea virus (BVDV) is responsible for significant losses to the cattle industry. Currently, modified-live viral (MLV) and inactivated viral vaccines are available against BVDV, often in combination with other viral and bacterial antigens.
Manuel F Chamorro +2 more
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Bovine viral diarrhea virus infections in heterologous species
Animal Health Research Reviews, 2009AbstractInfections with Bovine viral diarrhea virus (BVDV) are not limited to cattle, but may be detected in various species in the mammalian order Artiodactyla. Despite epidemiological evidence of BVDV infections in species other than cattle, current knowledge regarding the impact of BVDV on heterologous species is incomplete.
Paul H. Walz, Thomas Passler
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Immunologic Response of Bovine Fetus to Bovine Viral Diarrhea Virus
American Journal of Veterinary Research, 1973SUMMARY Intraperitoneal inoculation of a cytopathogenic strain of bovine viral diarrhea-mucosal disease (bvd-md) virus, National Animal Disease Laboratory (NADL) strain, was performed in bovine fetuses at different stages of development to study their immunologic response to this virus. Results of morphologic, immunochemical, and serologic examinations
R K, Braun, B I, Osburn, J W, Kendrick
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EXPERIMENTAL INFECTION OF DEER WITH BOVINE VIRAL DIARRHEA VIRUS
Journal of Wildlife Diseases, 1997In order to determine the susceptibility of deer to infection with bovine viral diarrhea virus (BVDV), four mule deer (Odocoileus hemionus) fawns and one white-tailed deer (O. virginianus) fawn were inoculated intranasally with the New York-1 strain of BVDV originally isolated from cattle. None of the animals developed clinical signs of illness.
Glen Stout +4 more
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