Results 101 to 110 of about 11,768 (263)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Blood acid base, gas alterations and electrolyte changes in bovines with chronic traumatic reticuloperitonitis

Bulgarian Journal of Veterinary Medicine
The study evaluated blood acid base, gas alterations and electrolyte changes in twenty bovines with chronic traumatic reticuloperitonitis (TRP). Blood samples were collected by jugular venepuncture for blood gas and electrolyte analysis.
S. A. Hussain, S. K. Uppal
doaj   +1 more source

Balanço de nitrogênio e estimativas de perdas endógenas em vacas lactantes alimentadas com dietas contendo palma forrageira e teores crescentes de uréia e mandioca = Nitrogen balance and endogenous loss estimate in lactating cows fed with diets of forage cactus and increasing levels of urea and cassava

Acta Scientiarum: Animal Sciences, 2006
Foram avaliados os efeitos da substituição do farelo de soja pela mistura uréia mais mandioca, em rações constituídas de palma, silagem de sorgo e concentrado, sobre concentrações de uréia, balanço de nitrogênio (N) e estimativas de perdas endógenas ...
Maria Cláudia Soares Cruz, Antonia Sherlânea Chaves Véras, Marcelo de Andrade Ferreira, Ângela Maria Vieira Batista, Djalma Cordeiro dos Santos, Marcelo Iran de Souza Coelho   +5 more
doaj  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Algarroba Effects on Behavior and Dairy Production of Grazing Cows II. Rainy Season.

Revista de Producción Animal, 2016
The influence of arborization with algarroba (Prosopis juliflora SW) on behavior and dairy production of grazing cows was evaluated. The trial was made in the rainy season, and six enclosures per arborization treatment were used (low arborization, with 1-
Raúl V. Guevara Viera , Alex J. Roca Cedeño , Paola J. Lascano Armas , Cristian N. Arcos Álvarez , Jhon C. Vera Cedeño , Guillermo E. Guevara Viera , Lino M. Curbelo Rodríguez , Diego A. Galarza Lucero , Servando A. Soto Senra   +8 more
doaj  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source