Results 101 to 110 of about 827,558 (366)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Parsnip phytobezoar causing small bowel obstruction

open access: yesJournal of Pediatric Surgery Case Reports, 2019
Pediatric phytobezoars are a rare occurrence in the pediatric population and infrequently result in the need for surgical intervention. We report a rare case of an infant presenting with a small bowel obstruction that, on operative exploration revealed ...
Denise I. Garcia   +2 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

A Comprehensive Review of Vitamin C for Cancer Therapy: Anti-Tumor Mechanisms and Nano-Formulation Strategies

open access: yesInternational Journal of Nanomedicine
Pinxu Ge,1 Xiaomei Tao,1 Jinxiu Qu,1 Jia He,1 Chenqi Xing,2 Shiwan Wang,1 Yuan Zhao,1 Shijie Yu,1 Jiqiang Xu,1 Liang Wang,1 Yuru Li,1 Xin Wang,1 Benqiang Rao1 1Department of Peritoneal Tumor and Malignant Bowel Obstruction Surgery, Beijing Shijitan ...
Ge P   +12 more
doaj  

Appendiceal knotting causing small bowel strangulation

open access: yesJournal of Research in Medical Sciences, 2014
Small bowel obstruction is a common cause of an emergency admission in the surgical wards. Acute appendicitis presenting with small bowel obstruction due to appendiceal knotting is a very rare and unsuspected condition in an emergency scenario. We report
Chandan Chatterjee   +3 more
doaj  

Primary Signet-Ring Carcinoma (Linitus Plastica) of the Colorectum presenting as Subacute Intestinal Obstruction [PDF]

open access: yes, 2012
Primary Signet-ring cell carcinoma (Linitus Plastica) of the colon and rectum is a rare form of adenocarcinoma of the large intestine and has been reported to have an extremely poor prognosis. We report a case of Primary Signet-ring cell carcinoma of the
Jagtap, SS   +4 more
core  

Cytological Findings of 140 Bile Samples from Dogs and Cats and Associated Clinical Pathological Data [PDF]

open access: yes, 2015
BACKGROUND: Cholecystocentesis can be part of the diagnostic workup of hepatobiliary disease in small animals, but literature on cytological evaluation of bile is scant.
Boomkens   +16 more
core   +2 more sources

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

A Study on Clinical Profile & Management of Acute Intestinal Obstruction [PDF]

open access: yesWalawalkar International Medical Journal, 2017
Acute intestinal obstruction is a failure of aboral progression of intestinal contents. The overall mortality and morbidity of bowel obstruction is substantial.
Abhijeet Patil, Dhirendra Wagh
doaj  

Learning Cultural Humility Through Stories and Global Service-Learning

open access: yes, 2018
Service-learning experiences are often utilized by nursing programs in efforts to increase the cultural competence of nursing students. Through the use of sharing story, the concepts of cultural competence and cultural humility can be explained for ...
Fisher, Stephanie   +2 more
core   +1 more source

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