Results 101 to 110 of about 822,233 (374)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Appendiceal knotting causing small bowel strangulation

open access: yesJournal of Research in Medical Sciences, 2014
Small bowel obstruction is a common cause of an emergency admission in the surgical wards. Acute appendicitis presenting with small bowel obstruction due to appendiceal knotting is a very rare and unsuspected condition in an emergency scenario. We report
Chandan Chatterjee   +3 more
doaj  

In-hospital costs of an admission for adhesive small bowel obstruction

open access: yesWorld Journal of Emergency Surgery, 2016
BackgroundPrevious research on the costs of treatment for ASBO is outdated and often based on reimbursements, rather than true healthcare provider costs of the admission and related interventions.
P. Krielen   +5 more
semanticscholar   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

A Study on Clinical Profile & Management of Acute Intestinal Obstruction [PDF]

open access: yesWalawalkar International Medical Journal, 2017
Acute intestinal obstruction is a failure of aboral progression of intestinal contents. The overall mortality and morbidity of bowel obstruction is substantial.
Abhijeet Patil, Dhirendra Wagh
doaj  

Learning Cultural Humility Through Stories and Global Service-Learning

open access: yes, 2018
Service-learning experiences are often utilized by nursing programs in efforts to increase the cultural competence of nursing students. Through the use of sharing story, the concepts of cultural competence and cultural humility can be explained for ...
Fisher, Stephanie   +2 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Radiological Techniques in the Diagnosis of Strangulating Small Bowel Obstruction

open access: yesJournal of Nepal Medical Association, 2013
Objective: Early detection of signs of strangulation in case of acute small bowel obstruction is critical because it mandates an operation. So, the role of different available radiological techniques used for diagnosing strangulating SBO is reviewed ...
Ashwini kumar Jha
doaj   +3 more sources

Removal of a phytobezoar through exploratory laparoscopy: a case of small bowel obstruction

open access: yesOpen Access Surgery, 2010
Brian Nguyen1, Andrew Barleben2, Brian S Buchberg2, Michael J Stamos2, Steven Mills21Department of Biological Sciences, 2Department of Surgery, Division of Colon and Rectal Surgery, University of California, Irvine, CA, USAAbstract: Small bowel ...
Brian Nguyen   +3 more
doaj  

Uncommon Metastasis of Laryngeal Cancer to Small Bowel Causing Intestinal Obstruction Treated by Laparoscopic Approach

open access: yesCase Reports in Surgery, 2014
Metastatic laryngeal cancer to the small bowel is extremely rare. Management of small bowel obstruction used to constitute a relative contraindication for the use of laparoscopic modality. We are reporting a case of an elderly man known to have laryngeal
Omar Bekdache   +5 more
doaj   +1 more source

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