Results 241 to 250 of about 171,393 (337)

A Peripheral Mechanism of Depression: Disturbed Intestinal Epithelial Per2 Gene Expression Causes Depressive Behaviors in Mice with Circadian Rhythm Disruption via Gut Barrier Damage and Microbiota Dysbiosis

open access: yesAdvanced Science, EarlyView.
Circardian rhythm disorder (CRD) causes abnormal expression of intestinal Period 2 (Per2) gene, which compromising intestinal barrier integrity and altering the gut microenvironment. Microbiota dysbiosis and aberrant metabolites production drive central inflammation, impair neurogenesis, and promote functional deficits, ultimately facilitating the ...
Huiliang Zhang   +16 more
wiley   +1 more source

The knotted appendix: an unusual cause of bowel obstruction: a case report. [PDF]

open access: yesJ Surg Case Rep
Belay SA   +6 more
europepmc   +1 more source

Prenatal diagnosis of fetal bowel obstruction complicated by in utero acute intestinal perforation [PDF]

open access: bronze, 2003
Roberto Méndez‐Gallart   +6 more
openalex   +1 more source

Single‐Cell Transcriptomics Unravels Growth Factor Erv1‐Like Mediated Ferroptosis as a Key Driver of Intestinal Epithelial Dysfunction in Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
Single‐cell transcriptomic profiling of ulcerative colitis (UC) tissues identified downregulation of GFER in intestinal epithelial cells. Mechanistically, GFER interacts with PCBP1 to help maintain intracellular iron homeostasis and may also reduce lipid peroxidation by activating the PGC‐1α/PPARγ signaling pathway, thereby inhibiting ferroptosis ...
Ya Song   +5 more
wiley   +1 more source

Risk of small bowel obstruction (SBO) following the pelvic pouch procedure (PP)

open access: bronze, 2000
Anthony R. MacLean   +6 more
openalex   +1 more source

Late small bowel obstruction after blunt abdominal trauma [PDF]

open access: bronze, 2003
Dungala Dileep Maharaj   +3 more
openalex   +1 more source

Dynamic Arginine Methylation of YBX1 Relay Controls Its Phase Separation and Chemoradiotherapy Resistance in Rectal Cancer

open access: yesAdvanced Science, EarlyView.
Protein arginine methyltransferase 3 (PRMT3) induces the arginine methylation of Y‐box binding protein 1 (YBX1), which suppresses phase separation and is imperative for its nuclear translocation. Subsequently, lysine‐specific demethylase 4A demethylates YBX1 to unmask the R247 residue and promote its phase separation, which transcriptionally regulates ...
Yunxing Shi   +11 more
wiley   +1 more source

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