Results 61 to 70 of about 171,393 (337)
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
A postoperative complication: Untangling iatrogenic rotation at the ligament of Treitz
Radiology Case ReportsIatrogenic small bowel obstruction is rare. Cases of proximal small bowel obstruction caused by the rotation of the distal duodenum around the ligament of Treitz are even rarer.
Hadir Elbeltagi, BMBS, BSc +3 more
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Clinical Case Reports, 2023 Key Clinical Message Peritoneal encapsulation is most of the time asymptomatic and is found incidentally, but when symptomatic it usually presents with bowel obstruction. CT scan is a gold standard for the diagnosis of bowel encapsulation.
Seyed Hossein Hajimirzaei +6 more
doaj +1 more source
Crohn's disease activity index and Vienna classification - Is it worthwhile to calculate before surgery? [PDF]
, 2006 Background: Crohn's disease (CD) patients with increased disease activity may reveal an increased risk for perioperative complications. The `Crohn's disease activity index' (CDAI) and the `Vienna classification' (VC) were developed for standardized ...
A. Beham +29 more
core +1 more source
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Small bowel obstruction secondary to foam earplug ingestion
Journal of Pediatric Surgery Case Reports, 2020 We describe a case of a 12 month old male who presented with small bowel obstruction (SBO) secondary to ingestion of a foam ear plug. Both X-ray and ultrasound failed to pick up the cause of obstruction.
Duncan McGrouther +2 more
doaj +1 more source
A Rare Case of Foreign Body Ingestion, Mimicking as Mesenteric Cyst. "Case Report" [PDF]
, 2020 Background: Foreign body ingestion by children is a commonly encountered problem and accounts for a significant emergency visits among pediatric population.
Hashim, I. (Imran) +5 more
core
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source