Results 41 to 50 of about 151,880 (263)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Effectiveness of using a patient education mobile application to improve the quality of bowel preparation: a randomised controlled trial

BMJ Open Gastroenterology, 2023
Aims To determine the effectiveness of a mobile application (app) in improving the quality of bowel preparation for colonoscopy.Method An endoscopist-blinded randomised controlled trial enrolled patients who were undergoing a colonoscopy on the same day ...
Jeroan Allison, Thuy Thi Nguyen, Hang Viet Dao, Long Van Dao, Quan Viet Dao, Hoa Ngoc Lam, Long Bao Hoang, Van Thi Nguyen, Dat Quoc Vu, Christopher S Pokorny, Hoa Lan Nguyen, Robert Joel Goldberg, An Thi Minh Dao, Toan Thanh Thi Do   +13 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Meta-Analysis of the Effect of Bowel Preparation on Adenoma Detection: Early Adenomas Affected Stronger than Advanced Adenomas. [PDF]

PLoS ONE, 2016
Low-quality bowel preparation reduces efficacy of colonoscopy. We aimed to summarize effects of bowel preparation on detection of adenomas, advanced adenomas and colorectal cancer.A systematic literature search was performed regarding detection of ...
Michael C Sulz, Arne Kröger, Meher Prakash, Christine N Manser, Henriette Heinrich, Benjamin Misselwitz   +5 more
doaj   +1 more source

Split dose bowel preparation before colonoscopy of PEG (Nulytely) in comparison to routine single dose bowel preparation

The Saudi Journal of Gastroenterology, 2021
Background: The aim of this study was to compare the efficacy and tolerability of polyethylene glycol (PEG) in single- or split-dose regimens for colonoscopy bowel preparation.
Said Al Alawi, Hisham Al Dhahab, Issa Al Salmi   +2 more
doaj   +1 more source

Validating bowel preparation scales [PDF]

Endoscopy International Open, 2017
Abstract Background and study aim Few scales assessing bowel preparation quality have been validated, and direct between-scale comparisons remain scarce. The aim of the study was to compare inter- and intra-rater reliability, predictive abilities for clinical outcomes, and ease of use for each scale.
Valérie Heron, Robin Parmar, Charles Ménard, Myriam Martel, Alan N. Barkun   +4 more
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Effect of Functional Status on the Quality of Bowel Preparation in Elderly Patients Undergoing Screening and Surveillance Colonoscopy

Gut and Liver, 2016
Background/AimsOptimal bowel preparation is essential for successful screening or for surveillance colonoscopy (SC). Inadequate bowel preparation is associated with older age, the male gender, and the presence of certain comorbidities.
Akash Kumar, Lisa Lin, Oren Bernheim, Emilia Bagiella, Lina Jandorf, Steven H. Itzkowitz, Brijen J. Shah   +6 more
doaj   +1 more source

The effects of enteral nutrition in the bowel preparation in patients with diabetes mellitus

Journal of Integrative Nursing, 2020
Objective: The objective of the study was to investigate the effect of enteral nutrients in diabetic patients with fibrocolonoscopy. Materials and Methods: A total of 58 diabetic patients undergoing fibrocolonoscopy from January 2017 to December 2017 ...
Xiu-Li Ou, Yu-Zhen Chen, Min Zhang, Li-Zhen Lyu   +3 more
doaj   +1 more source