Results 41 to 50 of about 151,158 (263)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Risk Factors and Incidence of Poor Bowel Preparation in Elderly Patients: Prospective Study [PDF]

Folia Medica, 2019
Aim: The aim of this study was to identify the incidence of and the risk factors for poor bowel preparation in elderly patients.Patients and methods: We enrolled 240 patients over 60 years of age, hospitalized in the Clinic of Gastroenterology, Kaspela ...
Daniel Doykov, Vladimir Andonov
doaj   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Effect of Functional Status on the Quality of Bowel Preparation in Elderly Patients Undergoing Screening and Surveillance Colonoscopy

Gut and Liver, 2016
Background/AimsOptimal bowel preparation is essential for successful screening or for surveillance colonoscopy (SC). Inadequate bowel preparation is associated with older age, the male gender, and the presence of certain comorbidities.
Akash Kumar, Lisa Lin, Oren Bernheim, Emilia Bagiella, Lina Jandorf, Steven H. Itzkowitz, Brijen J. Shah   +6 more
doaj   +1 more source

Addition of Prucalopride to Standard Bowel Preparation Does Not Improve Colonic Mucosa Visualization—A Retrospective Observational Cohort Study

Journal of Digestive Endoscopy, 2022
Background Colonoscopy is currently gold standard for visualizing colonic mucosa. Presence of constipation is generally associated with poor bowel preparation.
Gaurav Kr Singh, Shamshersingh G. Chauhan, Saiprasad S. Lad, Pratik R. Sethiya, Mayur G. Gattani, Swapnil Walke, Mit Shah, Vikas R. Pandey, Meghraj A. Ingle   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The effects of enteral nutrition in the bowel preparation in patients with diabetes mellitus

Journal of Integrative Nursing, 2020
Objective: The objective of the study was to investigate the effect of enteral nutrients in diabetic patients with fibrocolonoscopy. Materials and Methods: A total of 58 diabetic patients undergoing fibrocolonoscopy from January 2017 to December 2017 ...
Xiu-Li Ou, Yu-Zhen Chen, Min Zhang, Li-Zhen Lyu   +3 more
doaj   +1 more source

Effectiveness of using a patient education mobile application to improve the quality of bowel preparation: a randomised controlled trial

BMJ Open Gastroenterology, 2023
Aims To determine the effectiveness of a mobile application (app) in improving the quality of bowel preparation for colonoscopy.Method An endoscopist-blinded randomised controlled trial enrolled patients who were undergoing a colonoscopy on the same day ...
Jeroan Allison, Thuy Thi Nguyen, Hang Viet Dao, Long Van Dao, Quan Viet Dao, Hoa Ngoc Lam, Long Bao Hoang, Van Thi Nguyen, Dat Quoc Vu, Christopher S Pokorny, Hoa Lan Nguyen, Robert Joel Goldberg, An Thi Minh Dao, Toan Thanh Thi Do   +13 more
doaj   +1 more source

Bowel Preparation: Current Status [PDF]

Clinics in Colon and Rectal Surgery, 2009
Despite emerging evidence from randomized controlled trials and meta-analyses questioning its use, mechanical bowel preparation (MBP) continues to hold an accepted place among surgeons. MBP has been administered to patients for over a century, and though the methods and agents used for intestinal cleansing have evolved over time, many surgeons still ...
James E, Duncan, Christie M, Quietmeyer
openaire   +2 more sources