Results 81 to 90 of about 32,873 (169)

Analytical Quality by Design‐Guided Optimisation and Validation of a Short‐Run Stability‐Indicating Reverse‐Phase Ultra‐Fast Liquid Chromatography (RP‐UFLC) Method for the Quantitation of Nonivamide

open access: yesBiomedical Chromatography, Volume 40, Issue 5, May 2026.
ABSTRACT Nonivamide (NON), a capsaicin analogue with similar pharmacological effects, is used in pain management, yet limited information exists on its accurate quantification by reverse‐phase liquid chromatography. A cost‐effective, efficient and precise RP‐HPLC method was developed, optimised using response surface methodology (central composite ...
Phindile Mahlangu   +3 more
wiley   +1 more source

Optimization of Selenite Removal by Lactobacillus sp. Tra cheese 6 Using Box-Behnken Design [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2016
Background & Aims: High concentrations of selenite have carcinogenetic, cytotoxic and genotoxic effects. Therefore, removal of this toxic pullutant from the environment has a particular importance in maintaining public health. In this study, with the aim
Morahem Ashengroph, Davoud Saedi
doaj  

LOGICAL AND EXPERIMENTAL DESIGN FOR PHENOL DEGRADATION USING IMMOBILIZED ACINETOBACTER SP. CULTURE

open access: yesInternational Islamic University Malaysia Engineering Journal, 2010
Phenol degradation processes were conducted through a series of enzymatic reactions effects and is affect by different components of the microbial metabolic flux.
Amro Abd Al Fattah Amara   +1 more
doaj   +1 more source

Surrogate modeling of RF circuit blocks [PDF]

open access: yes, 2010
Surrogate models are a cost-effective replacement for expensive computer simulations in design space exploration. Literature has already demonstrated the feasibility of accurate surrogate models for single radio frequency (RF) and microwave devices ...
Croon, Jeroen A   +3 more
core   +1 more source

Portable Photobioreactor‐Based Stock Culture of Skeletonema costatum for Sustainable Live Feed Production in Shrimp Hatcheries of Bangladesh

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
This study develops a portable photobioreactor in which Skeletonema costatum growth is optimized using Box‐Behnken design. The physico‐chemical parameters, such as temperature, salinity and pH are standardized to maximize culture duration and biomass production. The optimized biomass exhibits high protein content and essential fatty acids, particularly
Zahidul Islam   +3 more
wiley   +1 more source

Aplikasi Response Surface Methodology Pada Optimalisasi Kondisi Proses Pengolahan Alkali Treated Cottonii (ATC)

open access: yesJurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan, 2013
Alkali Treated Cottonii (ATC) merupakan hasil olahan rumput laut merah (Eucheuma cottonii) dengan perlakuan alkali. Kondisi proses seperti konsentrasi KOH, suhu dan waktu proses akan berpengaruh pada kuantitas dan kualitas ATC yang dihasilkan.
Sitti Nurmiah   +4 more
doaj   +1 more source

Removal of benzotriazole by Photo-Fenton like process using nano zero-valent iron: Response surface methodology with a Box-Behnken design [PDF]

open access: yes, 2017
In this paper, the removal of benzotriazole (BTA) was investigated by a Photo-Fenton process using nano zero valent iron (NZVI) and optimization by response surface methodology based on Box-Behnken method. Effect of operating parameters affecting removal
Ahmadi, M.   +3 more
core   +1 more source

A Design of Experiments‐Based Chiral HPLC Method for the Quantification of Talazoparib and Enantiomeric Purity Determination in Pharmaceutical Formulations

open access: yesChirality, Volume 38, Issue 4, April 2026.
A design of experiments–based chiral HPLC method was developed for the enantiomeric separation and quantification of talazoparib in pharmaceutical formulations. Efficient resolution of the enantiomers (RS > 7) was achieved within 12 min. The method was validated and successfully applied to tablet analysis, and its environmental sustainability was ...
Sakine Atila Karaca   +2 more
wiley   +1 more source

VRSTE PLANOVA EKSPERIMENTA ZA MODELIRANJE ZRAKOPROPUSNOSTI ZGRADA [PDF]

open access: yes, 2015
The paper presents experimental designs that can be used in modeling of the air-tightness of buildings as second-order functions using response surface method and corresponding experiment designs.
Ištoka Otković, Irena   +2 more
core   +4 more sources

Characterisation of Antisense Oligonucleotides by Ion‐Pair Reversed‐Phase UHPLC‐HRMS: Method development using Design of Experiments

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 4, April 2026.
ABSTRACT The quality control of therapeutic antisense oligonucleotides (ASOs) poses significant analytical challenges due to the complexity of their synthesis and degradation processes and the need to ensure the safety and efficacy of active pharmaceutical ingredients (APIs).
Antonio Triolo   +4 more
wiley   +1 more source

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