Results 51 to 60 of about 679,230 (229)

Formulation and characterization of ketoprofen liquisolid compacts by Box-Behnken design

International Journal of Pharmaceutical Investigation, 2012
Liquisolid technique is used in delivery of lipophilic and poorly water soluble drugs through oral route. It involves dissolving water insoluble drugs in nonvolatile solvents and converting into acceptably flowing and compressible powders. The objective of the present work was to enhance the dissolution rate of ketoprofen using microcrystalline ...
Vittal, G Vijayaranga, Deveswaran, R, Bharath, S, Basavaraj, BV, Madhavan, V   +4 more
openaire   +3 more sources

Sustainable levulinic acid production from inulin via hydrothermal conversion

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract This study investigates the hydrothermal conversion of inulin using potassium pyrosulfate to levulinic acid (LA). The Box–Behnken design approach was applied to optimize the conversion parameters and analyze the interactions influencing LA yield.
Gwi‐Taek Jeong
wiley   +1 more source

Box-Behnken experiment design and the results of the POP yield.

, 2019
Box-Behnken experiment design and the results of the POP yield.
Matiar Rahman (6172199), Md. Moyen Uddin Pk (6172184), Mohammad Sayful Islam (6172187), Rabiul Islam Talukder (6172196), Rumana Pervin (6172190), Subhajit Dutta (6172193)   +5 more
core   +1 more source

Optimization of Combined Pre-Treatment Process for Bleaching of Cotton Woven Fabric Using Box–Behnken Design

Journal of Natural Fibers
The conventional bleaching process for cotton woven fabrics is characterized by high consumption of chemicals, water, and energy, resulting in significant environmental impact through elevated energy use and wastewater discharge.
Bantamlak Birlie Kassie, Habtamu Fentahun, Tekalgn Mamay Daget   +2 more
doaj   +1 more source

Optimization of paclitaxel loaded poly (ε-caprolactone) nanoparticles using Box Behnken design

Beni-Suef University Journal of Basic and Applied Sciences, 2017
Optimization is a critical process in the development of nanoparticles to apprehend the formulation variables and quality attributes. The purpose of this study was to evaluate the influence of formulation variables viz., drug/polymer ratio (A ...
Nandhakumar Sathyamoorthy, Dhanaraju Magharla, Pavankumar Chintamaneni, Sundar Vankayalu   +3 more
doaj   +1 more source

Dynamic, Unconstrained Optimization of Secreted Enzyme Production in Fed‐Batch Fermentation Using Reinforcement Learning

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Reinforcement learning (RL) has been used to control a wide range of dynamic processes, especially ones that are too complex to model well or have stochastic environmental perturbations. Fed‐batch fermentations are subject to changes in starting cell growth rates and process variations that can affect cell growth and secreted target production.
Sai Harish Uthravalli, Sakib Ferdous, J. Michael Hess, Nigel F. Reuel   +3 more
wiley   +1 more source

Box-Behnken design and experimental values of induced airflow velocity (Y₁) and dust concentration (Y₂).

, 2022
Box-Behnken design and experimental values of induced airflow velocity (Y1) and dust concentration (Y2).
Qingjie Qi (9674147), Shaocheng Ge (11021598), Chaonan Fan (9030155), Xi Chen (35903)   +3 more
core   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source

Box-Behnken design with coded levels of three independent variables and experimental vs. predicted POS.

, 2016
Box-Behnken design with coded levels of three independent variables and experimental vs. predicted POS.
Ahmed Hussein (683680), Amal H. El-Kamel (3592073), Amira M. Embaby (3592067), Ramy R. Melika (3592070), Heba S. Marey (3592076)   +4 more
core   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source