Results 131 to 140 of about 13,345 (178)
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Box-Behnken Design: An Alternative for the Optimization of Analytical Methods
Analytica Chimica Acta, 2007The present paper describes fundamentals, advantages and limitations of the Box-Behnken design (BBD) for the optimization of analytical methods. It establishes also a comparison between this design and composite central, three-level full factorial and Doehlert designs.
Jorge M David +2 more
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Statistics & Probability Letters, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Zhang, Tian-Fang +2 more
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zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Zhang, Tian-Fang +2 more
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Linear trend-free Box–Behnken designs
Journal of Statistical Planning and Inference, 1998zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hinkelmann, Klaus, Jo, Jinnam
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Isolation of Degrees of Freedom for Box—Behnken Designs
Technometrics, 1994The Box–Behnken three-level designs have proved useful for fitting second-order response surfaces to experimental data. Here, we discuss an aspect of their value in the detection of lack of model fit. The degrees of freedom in excess of those needed to fit the model can be used advantageously for contrasts which estimate certain higher-order departures
Norman R. Draper +3 more
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Small Box–Behnken designs with orthogonal blocks
Statistics & Probability Letters, 2014zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Pham, Tung-Dinh, Nguyen, Nam-Ky
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Box–Behnken Designs and Their Applications in Pharmaceutical Product Development
2021Box–Behnken designs (BBDs) are the very efficient response surface design which provides information exclusively on the effect of experiment variables and overall experimental error in a minimum number of required runs. These designs possess very good symmetry and rotatability and also produce minimal experimental runs, as compared to the popular CCD ...
Sarwar Beg, Sohail Akhter
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Optimization and development of antidiabetic phytosomes by the Box–Behnken design
Journal of Liposome Research, 2017Researchers have extensively reviewed on herbs and natural products for their marked clinical efficacy in some recent years, however, maximum of the newly discovered bioactive constituents offer poor bioavailability due to their large size molecules or to their poor miscibility with oils and lipids, thereby limiting their ability to pass across the ...
Sushila, Rathee, Anjoo, Kamboj
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Box-Behnken experimental design for the production of precipitated calcium carbonate
Pure and Applied Chemistry, 2016Abstract Calcium carbonate (CaCO3) was synthesized by means of ultrasonic process in the presence of the water-soluble polymer carboxymethyl inulin (CMI). Synthesized CaCO3 crystals were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and BET (Brunauer, Emmett and Teller) isotherm.
Dogan, Ozlem +2 more
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Formulation and optimization of rifampicin microparticles by Box-Behnken statistical design
Pharmaceutical Development and Technology, 2011The objective of the present study was to optimize and evaluate in vitro gastroretentive performance of rifampicin microparticles. Formulations were optimized using design of experiments by employing a 4-factor, 3-level Box-Behnken statistical design. Independent variables studied were the ratio of polymers (Eudragit RSPO: ethyl cellulose), inert drug ...
D P, Maurya +3 more
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Microbiological improvement of soils with Box–Behnken experimental design
Acta GeophysicaKaradeniz Teknik niversitesi [FDK-2022-10406]; Scientific Research Projects Coordination Unit of Karadeniz Technical University -- We would like to express our gratitude to the Scientific Research Projects Coordination Unit of Karadeniz Technical University, which provided the funding for this study (Project ID: FDK-2022-10406/Determination of ...
Zehra Ertosun Karabulut +2 more
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