Results 41 to 50 of about 148,855 (265)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Research on the Model Improvement of a DLA Fractal River Network
IEEE Access, 2020 Computer simulations are introduced into the river dynamics field to provide a basis for studying fractal river networks. This paper improved on the defects of particle aggregation and growth methods in the standard diffusion-limited aggregation (DLA ...
Shengwei Wang +4 more
doaj +1 more source
Box dimension of the border of Kingdom of Saudi Arabia
Heliyon, 2023 Fractal dimension unlike topological dimension is (usually) a non-integer number which measures complexity, roughness, or irregularity of an object with respect to the space in which the set lies.
Mohammad Sajid +5 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Fractal and FractionalVolcanic rocks, as a widely distributed rock type on the earth, are mostly buried deep within basins, and their internal structures possess characteristics by irregularity and self-similarity.
Sijia Li, Zhuwen Wang, Dan Mou
doaj +1 more source
Fractal Characteristic of Rock Cutting Load Time Series
Discrete Dynamics in Nature and Society, 2014 A test-bed was developed to perform the rock cutting experiments under different cutting conditions. The fractal theory was adopted to investigate the fractal characteristic of cutting load time series and fragment size distribution in rock cutting.
Hongxiang Jiang +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Box-counting dimensions of generalised fractal nests [PDF]
Chaos, Solitons & Fractals, 2018 Fractal nests are sets defined as unions of unit $n$-spheres scaled by a sequence of $k^{-α}$ for some $α>0$. In this article we generalise the concept to subsets of such spheres and find the formulas for their box counting dimensions. We introduce some novel classes of parameterised fractal nests and apply these results to compute the dimensions ...
openaire +3 more sources