Results 61 to 70 of about 42,178 (311)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

[News Clip: Kid boxing] [PDF]

open access: yes, 1959
Video footage from the WBAP-TV station in Fort Worth, Texas to accompany a news story about the first annual Compton Citadel Invitational Junior Gloves boxing tournament in ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Globalizing Boxing [PDF]

open access: yes, 2014
Globalizing Boxing uses boxing as a vehicle for exploring globalizing social cultural political and economic change. Boxing, although deeply embedded in enduring racialised, gendered practices contributes to social transformations as well as reflecting ...
Woodward, Kath
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Boxing and Neuroethics

open access: yesVoices in Bioethics, 2014
“If boxing is a sport it is the most tragic of all sports … it consumes the very excellence it displays.” Joyce Carol Oates, On Boxing Muhammad Ali has Parkinson’s disease. Ken Norton barely speaks and moves slowly using a walker.
Stephanie Holmquist
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Portrait of Colin Fitzjohn in boxing pose [picture] [PDF]

open access: yes, 1900
Part of: Arnold Thomas boxing collection.; Title devised by cataloguer from handwritten inscription on reverse.; Inscription: "Boxing, Colin Fitzjohn"--Handwritten in pencil on reverse.; Condition: Good.; Also available in an electronic version via the ...

core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Johnny Hutchinson in a boxing ring [picture] [PDF]

open access: yes, 1930
Inscriptions: "Johnie Hutchinson U.S.A. had many bouts in Australia in the 1930's"--In ink, on reverse.; Part of: Arnold Thomas boxing collection.; Title devised by cataloguer.; Also available in electronic version via the Internet at: http://nla.gov.au ...

core  

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