Results 181 to 190 of about 243,792 (206)

Effects of bioaugmentation by isolated Achromobacter xylosoxidans BP1 on PAHs degradation and microbial community in contaminated soil.

Journal of Environmental Management, 2023
Polycyclic aromatic hydrocarbons (PAHs) are a group of organic pollutants ubiquitous and persistent in soil. In order to provide a viable solution for bioremediation of PAHs-contaminated soil, a strain of Achromobacter xylosoxidans BP1 with superior PAHs
Ben Zhang, Wei Xu, Yichi Ma, Xiaolong Gao, Huyang Ming, Jianli Jia   +5 more
semanticscholar   +1 more source

The mTOR/4E-BP1/eIF4E signalling pathway as source of cancer drug targets.

Current Medicinal Chemistry, 2022
The mechanistic/mammalian target of rapamycin (mTOR) is the crucial hub of signalling pathways that regulate essential steps in the cell life cycle. Once incorporated in the mTORC1 complex, mTOR phosphorylates the eukaryotic initiation factor 4E (eIF4E)-
C. Maracci, S. Motta, A. Romagnoli, Matteo Costantino, P. Perego, D. Di Marino   +5 more
semanticscholar   +1 more source

Nuclear-targeted 4E-BP1 is dephosphorylated, induces nuclear translocation of eIF4E, and alters mRNA translation.

Experimental Cell Research, 2022
Mechanistic target of rapamycin complex 1 (mTORC1) phosphorylates and inhibits eukaryotic translation initiation factor 4E (eIF4E)-binding protein 1 (4E-BP1).
S. Takahashi, Shusaku Shibutani, Hiroyuki Iwata   +2 more
semanticscholar   +1 more source

PP2A-mTOR-p70S6K/4E-BP1 axis regulates M1 polarization of pulmonary macrophages and promotes ambient particulate matter induced mouse lung injury.

Journal of Hazardous Materials, 2021
To identify key signaling pathways involved in ambient particulate matter (PM)-induced pulmonary injury, we generated a mouse model with myeloid-specific deletion of Ppp2r1a gene (encoding protein phosphatase 2 A (PP2A) A subunit), and conducted ...
Shen Chen, Li-ping Chen, Lizhu Ye, Yue-ming Jiang, Qiong Li, Haiyan Zhang, Rui Zhang, Huiyao Li, Dianke Yu, Rong Zhang, Yu-jie Niu, Qun Zhao, Jianhui Liu, Gangfeng Ouyang, M. Aschner, Yu-xin Zheng, Lihua Zhang, Wen Chen, Daochuan Li   +18 more
semanticscholar   +1 more source

BP1, a Potential Biomarker for Breast Cancer Prognosis

Biomarkers in Medicine, 2018
Homeobox genes are critical in tumor development. An isoform protein of DLX4 called BP1 is expressed in 80% of invasive ductal breast carcinomas. BP1 overexpression is implicated in an aggressive phenotype and poor prognosis.
Yassi Fallah, Patricia E Berg
exaly   +2 more sources

A bright γ-ray flare interpreted as a giant magnetar flare in NGC 253

Nature, 2021
Soft γ-ray repeaters exhibit bursting emission in hard X-rays and soft γ-rays. During the active phase, they emit random short (milliseconds to several seconds long), hard-X-ray bursts, with peak luminosities1 of 1036 to 1043 erg per second. Occasionally,
D. Svinkin, D. Frederiks, K. Hurley, R. Aptekar', S. Golenetskii, A. Lysenko, A. Ridnaia, A. Tsvetkova, M. Ulanov, T. Cline, I. Mitrofanov, D. Golovin, A. Kozyrev, M. Litvak, A. Sanin, A. Goldstein, M. Briggs, C. Wilson-Hodge, A. von Kienlin, X. Zhang, A. Rau, V. Savchenko, E. Bozzo, C. Ferrigno, P. Ubertini, A. Bazzano, J. Rodi, S. Barthelmy, J. Cummings, H. Krimm, D. Palmer, W. Boynton, C. Fellows, K. Harshman, H. Enos, R. Starr   +35 more
semanticscholar   +1 more source

The dominant role of extracellular polymeric substances produced by Achromobacter xylosoxidans BP1 in Cr(VI) microbial reduction.

Science of the Total Environment
Extracellular polymeric substances (EPS) have demonstrated significant benefits for reducing multivalent metal contamination. Using Achromobacter xylosoxidans BP1 isolated from a coal chemical site in China, this study elucidated the contribution of EPS ...
Jianli Jia, Bing Xiao, Linying Yao, Ben Zhang, Yichi Ma, Weiran Wang, Yuxin Han, Qiushuang Lei, Ruofan Zhao, Jingqi Dong, Nan Wei, Hongzhe Zhang   +11 more
semanticscholar   +1 more source

Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1

FEBS Letters, 2004
Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) represses translation initiation by binding to eukaryotic initiation factor 4E (eIF4E). 4E-BP1 also binds to the eIF4E homologous protein (4EHP).
Andrew R Tee, John Blenis
exaly   +2 more sources

Detection of a novel familial deletion of four genes between BP1 and BP2 of the Prader-Willi/Angelman syndrome critical region by oligo-array CGH in a child with neurological disorder and speech impairment

Cytogenetic and Genome Research, 2007
S. Murthy, A. Nygren, H. M. E. Shakankiry, J. Schouten, A. Khayat, A. Ridha, M. Ali   +6 more
semanticscholar   +1 more source

253 PrecisionGluco squad: an initiative for effective blood glucose monitoring for patients on enteral bolus feeding

253 PrecisionGluco squad: an initiative for effective blood glucose monitoring for patients on enteral bolus feeding
Junjiao Yu, E. Liow, Er Boon Hui, C. Ling, Daphne Gardner Tan Su-Lyn   +4 more
semanticscholar   +1 more source