Results 151 to 160 of about 44,175 (160)
A novel USP4 inhibitor that suppresses colorectal cancer stemness by promoting β-catenin and Twist1 degradation. [PDF]
Li F +12 more
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Mitolnc controls cardiac BCAA metabolism and heart hypertrophy by allosteric activation of BCKDH. [PDF]
Weiss M +6 more
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A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments. [PDF]
Chidley C +6 more
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PAX2 induces endometrial cancer by inhibiting mitochondrial function via the CD133-AKT1 pathway. [PDF]
Hua F, Cai Y.
europepmc +1 more source
The pleiotropic spectrum of proximal 16p11.2 CNVs. [PDF]
Auwerx C, Kutalik Z, Reymond A.
europepmc +1 more source
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The mTOR/4E-BP1/eIF4E signalling pathway as source of cancer drug targets.
Current Medicinal Chemistry, 2022The mechanistic/mammalian target of rapamycin (mTOR) is the crucial hub of signalling pathways that regulate essential steps in the cell life cycle. Once incorporated in the mTORC1 complex, mTOR phosphorylates the eukaryotic initiation factor 4E (eIF4E)-
C. Maracci +5 more
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