Results 91 to 100 of about 181,909 (270)

Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression

Advanced Science, EarlyView.
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo, Xiaodong Chen, Haojia Wang, Jiying Zhou, Peiying Lu, Jiangying Liu, Keyan Chai, Jingyuan Zhang, Siyun Yang, Shan Lu, Yifei Gao, Zhengsen Jin, Xiaoyu Tao, Zhongdong Hu, Qinglin Li, Jiarui Wu   +15 more
wiley   +1 more source

Application of improved BP neural network in fault detection of mine ventilation system

Gong-kuang zidonghua, 2013
For problem that step of traditional learning algorithm of BP neural network is difficult to determine, the paper proposed a method of using BP neural network based on RLS algorithm to detect fault of mine ventilation system.
ZHANG Fei, HE Ya-qin, ZHANG Ke
doaj  

ADAS Simulation Result Dataset Processing Based on Improved BP Neural Network

Data
The autonomous driving simulation field lacks evaluation and forecasting systems for simulation results. The data obtained from the simulation of target algorithms and vehicle models cannot be reasonably estimated. This problem affects subsequent vehicle
Songyan Zhao, Lingshan Chen, Yongchao Huang   +2 more
doaj   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Application of back propagation neural network optimized by different algorithms in prediction of Mooney viscosity of ethylene-propylene-diene monomer compound

Hecheng xiangjiao gongye
Genetic algorithm (GA) and particle swarm optimization (PSO) were used to optimize the back propagation（BP） neural network to establish the prediction model of Mooney viscosity of ethylene-propylene-diene monomer (EPDM) compound, and the error of the ...
LI Gao-wei, LI Jia, ZHU Jin-mei, JIAN Ran-ran, MIAO Qing, ZENG Xian-kui
doaj   +1 more source

Research of pressure distribution model of coal slurry pipeline

Gong-kuang zidonghua, 2013
In view of nonlinear characteristic of pressure distribution of high viscous materials like coal slurry in slurry pipeline, the paper put forward a kind of modeling method based on BP neural network optimized by quantum genetic algorithm after analysis ...
WANG Xin-zhao, HOU Yuan-bin, YANG Xue-cun, DANG Jiao   +3 more
doaj   +1 more source

Neural Feedback Scheduling of Real-Time Control Tasks

, 2007
Many embedded real-time control systems suffer from resource constraints and dynamic workload variations. Although optimal feedback scheduling schemes are in principle capable of maximizing the overall control performance of multitasking control systems,
Dong, Jinxiang, Sun, Youxian, Tian, Yu-Chu, Xia, Feng   +3 more
core   +3 more sources

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Defect detection of wire rope for oil well based on adaptive angle

Fracture and Structural Integrity, 2015
This paper uses a digital image processing method which is based on texture feature of steel cable to detect the fracture of steel wire. At first, it uses a modified homomorphic filtering method to eliminate environment heterogeneous shining.
Zhang Jijun, Meng Xiangqing
doaj