Abstract Antigen‐processing and ‐presenting cells play a pivotal role in initiation of the antiviral immune response. The cellular adaption of dendritic cells to reduced oxygen and nutrition levels at the site of infection is regulated predominantly by the transcription factor complex hypoxia‐inducible factor‐1 (HIF‐1).
Timm Schreiber +8 more
wiley +1 more source
The Reality of Benign Prostatic Hyperplasia Surgery Price and Reimbursement Across Top United States Hospitals. [PDF]
Murray G +4 more
europepmc +1 more source
Therapeutic potential of spexin in diabetic neuropathy: Insights from in vitro and in vivo models
Abstract The present study investigated the therapeutic potential of spexin (SPX) on both in vitro and in vivo models of diabetic neuropathy (DN). A total of 40 male BALB/c mice were randomly allocated into four experimental groups (n = 10 per group): a normoglycaemic control, an untreated DN group and two SPX treatment groups (DN+SPX‐12.5 and DN+SPX ...
Mehmet Refik Bahar +5 more
wiley +1 more source
Protein kinase Cδ and pharmacomechanical coupling: Re‐envisioning cerebral vascular control
Abstract figure legend Top, G‐protein coupled receptors trigger electromechanical and pharmacomechanical coupling, the latter via signal transduction pathways that inhibit myosin light chain phosphatase. Middle, the relative contribution of electromechanical and pharmacomechanical coupling varies with the concentration and the vessel area to which ...
Nadia Haghbin +10 more
wiley +1 more source
Lipid and Foam Cell Accumulation as Novel Pathological Features of Benign Prostatic Hyperplasia. [PDF]
Julianingsih D +9 more
europepmc +1 more source
Abstract figure legend A high‐fat, high‐sucrose diet (HFHSD) exacerbated muscle and metabolic dysregulation in mdx mice while also altering the physiological response to prednisolone (Pred) In diaphragms of control diet (CD)‐fed mdx mice, prednisolone treatment improved muscle function and reduced fibrosis, inflammatory signalling, and mitochondrial ...
Morgan E. Vorwald +5 more
wiley +1 more source
Rice bran oil ameliorates the symptoms of benign prostatic hyperplasia in male Wistar rats. [PDF]
Miah MA +9 more
europepmc +1 more source
CaV1.2 dynamics in native male arterial myocytes
Abstract figure legend Proposed model of microtubule‐dependent CaV1.2 reorganization in vascular disease. Schematic illustration of microtubule‐mediated delivery and stabilization of CaV1.2 channels into enlarged plasma membrane clusters in response to Ang II or hyperglycaemia, promoting cooperative gating and enhanced Ca2+ influx. Abstract L‐type CaV1.
Miguel Martin‐Aragon Baudel +9 more
wiley +1 more source
Commentary: The impact of dietary inflammation index on benign prostatic hyperplasia: insights from patient data and animal models. [PDF]
Li Z, Wang L, Zhong L, Zheng D.
europepmc +1 more source
Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley +1 more source

