Results 41 to 50 of about 58,793 (273)

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

Advanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang, Yizhong Liang, Manan Sulaiman, Jiaqi Du, Ming Jiang, Zhihua Wang, Xu Yu, Li Xu   +7 more
wiley   +1 more source

The role of 5αR and α1AR inhibitors in management of BPH [PDF]

, 2019
BPH is a common progressive condition in the aging population. Several treatment modalities have been proposed aimed at inhibiting the sympathetic input to the prostate gland with a selective α1 adrenoreceptor inhibitor and interfering with the androgen ...
Khamaysi, Majd
core  

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

Renal nerves contribute to hypertension in Schlager BPH/2J mice [PDF]

, 2019
Schlager mice (BPH/2J) are hypertensive due to a greater contribution of the sympathetic nervous system (SNS) and renin-angiotensin system (RAS). The kidneys of BPH/2J are hyper-innervated suggesting renal nerves may contribute to the hypertension.
Fadi J. Charchar, Kristy L. Jackson, Gavin W. Lambert, Gueguen, Cindy, Phillips, Sarah, Francine Z. Marques, Davern, Pamela, Stevenson, Emily, Head, Geoffrey, Marques, Francine, Cindy Gueguen, Jackson, Kristy, Charchar, Fadi, Nina Eikelis, Eikelis, Nina, Lambert, Gavin, Sarah Phillips, Emily R. Stevenson, Geoffrey A. Head, Pamela J. Davern   +19 more
core   +2 more sources

PCSK9 inhibitors patterns of use in France from nationwide repeated cross-sectional and cohort studies

Scientific Reports
PCSK9 inhibitors (PCSK9i) are indicated in combination with statins and/or ezetimibe to intensify LDL-cholesterol lowering and reduce the risks of atherosclerotic cardiovascular disease.
Allison Singier, Anne Bénard-Laribière, Ana Jarne-Munoz, Antoine Pariente, Gwenaelle Veyrac, Julien Bezin   +5 more
doaj   +1 more source

The International Classification of Cognitive Disorders in Epilepsy (IC‐CoDE) Portal: An open source resource for neuropsychological research in epilepsy

Epilepsia, EarlyView.
Abstract Objective The International Classification of Cognitive Disorders in Epilepsy (IC‐CoDE) is a consensus‐based, empirically‐driven approach to standardize cognitive phenotyping in epilepsy research that has quickly garnered interest within the epilepsy community. However, manually generating IC‐CoDE phenotypes in group data is laborious and time‐
Robyn M. Busch, Tobias Brünger, Kayela Arrotta, Lisa Ferguson, Julie K. Janecek, Sara J. Swanson, Anny Reyes, Brook Hurd, Mark St. John, Carrie R. McDonald, Bruce P. Hermann, Dennis Lal   +11 more
wiley   +1 more source

Association of Lipopolysaccharide-Type Endotoxins with Retinal Neurodegeneration: The Alienor Study

Ophthalmology Science
Purpose: Lipopolysaccharide (LPS)-type endotoxins are naturally found in the gut microbiota and there is emerging evidence linking gut microbiota and neuroinflammation leading to retinal neurodegeneration. Thinning of the retinal nerve fiber layer (RNFL)
Petra P. Larsen, MD, Catherine Féart, PhD, Jean-Paul Pais de Barros, PhD, Laure Gayraud, MSc, Marie-Noëlle Delyfer, MD, PhD, Jean-François Korobelnik, MD, Cédric Schweitzer, MD, PhD, Cécile Delcourt, PhD   +7 more
doaj   +1 more source

Current surgical procedures for benign prostatic hyperplasia and impression of new surgical modalities

Urology Annals, 2021
Background : Surgery is considered the most effective treatment for Benign prostatic hyperplasia (BPH) and Transurethral resection of prostat (TURP) is considered the gold standard.
Abdullah M Al Khayal, Faisal K Balaraj, Turki A Alferayan, Khalid A Alrabeeah, Saad M Abumelha   +4 more
doaj   +1 more source

Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology

Exploration, EarlyView.
Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen, Wenzhe Yi, Rongzhang Li, Shuangshuang Hu, Xindi Qian, Dan Yan, Qian Zou, Guanru Wang, Yaping Li   +8 more
wiley   +1 more source

Modified laparoscopic simple prostatectomy combined with temporary internal iliac arteries clamping and urethrocystoanastomosis for large-volume benign prostatic hyperplasia: evaluation of efficacy and safety

Вестник урологии, 2023
Introduction. Laparoscopic simple prostatectomy is the method of choice for surgical treatment of large-volume benign prostatic hyperplasia (BPH).
S. N. Volkov, D. Yu. Pushkar, K. B. Kolontarev, V. S. Stepanchenko, V. I. Tereshchenko, A.  R. Dzharimok, E. N. Andreeva, O. R. Grigoryan, A. E.  Shevyakina, M. A. Daurov   +9 more
doaj   +1 more source