Results 251 to 260 of about 102,336 (308)

Prevention of microglial activation and postoperative cognitive deficits by positive allosteric modulation of α5‐GABAA receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Long‐lasting cognitive deficits after surgery in aged individuals, referred to as perioperative neurocognitive disorder (NCD), are a significant public health concern. Such postoperative cognitive deficits are dependent on the presence of microglia in the brain, which, when activated, trigger neuroinflammation.
Jinrui Lyu   +9 more
wiley   +1 more source

Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu   +5 more
wiley   +1 more source

The microbiome of interstitial cystitis revealed by 2bRAD-M. [PDF]

open access: yesSci Rep
Gan Y   +5 more
europepmc   +1 more source

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