Results 111 to 120 of about 379,220 (373)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

The ramosa1 gene plays a role in shoot-borne root patterning in Zea mays L. [PDF]

open access: yes, 2008
only availableMaize brace roots are the aerial portion of the shoot-borne root system that facilitates physical anchorage and water and nutrient acquisition. Shoot-borne roots develop from axillary meristems.
Aguayo, Moises   +2 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Unloading knee brace is a cost-effective method to bridge and delay surgery in unicompartmental knee arthritis

open access: yesBMJ Open Sport & Exercise Medicine, 2017
Background Unloading knee braces can provide good short-term pain relief for some patients with unicompartmental osteoarthritis (UOA). Their cost is relatively small compared with surgical interventions.
P. Lee   +4 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Compression fractures of the spine in children: isn’t it time to change something?

open access: yesХирургия позвоночника, 2019
Objective. To analyze the efficacy of various methods for treatment of children with compression fractures of the thoracic and lumbar spine on the basis of literature data. Material and Methods. A systematic review of the literature on methods for the
Nikita O. Khusainov   +1 more
doaj   +1 more source

The upper atmosphere and ionosphere of Mars [PDF]

open access: yes
The topics discussed include the following: the dynamic atmosphere of Mars; possible similarities with Earth and Venus; the atmosphere and ionosphere of Mars; solar wind interactions; future approved missions; and possible future ...
Brace, Larry H.
core   +1 more source

An Assessment of the Impact of Climate Change on Human Health in New Hampshire [PDF]

open access: yes, 2014
Climate change threatens human health in many ways. The negative impacts of climate change on human health are likely to increase in both magnitude and frequency as the climate continues to change in response to ever increasing global emissions of heat ...
Aytur, Semra   +2 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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