Results 11 to 20 of about 8,768 (167)

The Molecular and Immunological Landscape in Nasopharyngeal Carcinoma (NPC) Differs by Somatostatin Receptor 2 (SSTR2) Expression. [PDF]

Cancer Med
ABSTRACT Somatostatin receptor 2 is expressed in nasopharyngeal carcinoma (NPC). We report genomic and transcriptomic analysis results of 163 NPC cases, demonstrating that somatostatin receptor 2 (SSTR2) gene expression in EBV‐positive and in EBV‐negative NPC correlated with genomic alterations and an inflamed microenvironment.
Bracken-Clarke D, Xue E, Krause H, Adeyelu T, Evans MG, Akbulut D, Quezado M, Gandhi N, Farrell A, Soares HP, Lou E, Phan M, Patel R, Vanderwalde AM, Elliott A, Steuer CE, Saba NF, Lubin DJ, London NR, Gulley JL, Floudas CS.   +20 more
europepmc   +2 more sources

Improving Medication Safety Following Neonatal Discharge: A Feasibility Study of a Parent Medication Education Intervention in Ireland. [PDF]

Acta Paediatr
ABSTRACT Aim Neonates discharged home on medications remain at risk of medication errors. The PADDINGToN programme previously developed parent co‐designed resources to support safer medication administration following discharge. The aim of this study, PADDINGToN‐2, is to evaluate the feasibility of recruiting and retaining parents in a study assessing ...
Giva S, Cleary B, Gaffney F, Bracken L, Gill A, Sutton C, Clark J, Gray V, McCallion N, O'Brien F.   +9 more
europepmc   +2 more sources

Outcomes in progressive pulmonary fibrosis in systemic autoimmune rheumatic diseases: real‐world data from the ILD‐PRO Registry

Arthritis &Rheumatology, Accepted Article.
Objective We evaluated baseline characteristics, treatment patterns, and outcomes in patients with systemic autoimmune rheumatic disease‐associated progressive pulmonary fibrosis (SARD‐PPF) and evaluated whether outcomes differed by SARD subtype. Methods The ILD‐PRO Registry is a prospective multicenter US registry of patients with PPF.
Sonali J Bracken, Jeremy M Weber, Megan L Neely, Aparna C Swaminathan, Scott M Palmer, Erin M Wilfong, Ann D Chauffe, Elizabeth R Volkmann   +7 more
wiley   +1 more source

Continental scale metagenomics reveals Microcystis‐induced synchrony among aquatic taxa is exacerbated by trophic cascades

Ecography, EarlyView.
Harmful Microcystis proliferation severely threatens aquatic ecosystems globally, but its impacts on food‐web stability remain poorly understood. Here, we analyzed 1309 metagenomic samples from freshwater ecosystems across China to investigate how Microcystis abundance affects synchrony among taxa in multi‐trophic food webs (from bacteriophages to ...
Lemian Liu, Siqi Zhu, Xiaoqin Huang, Wenjia Hu, Lixiang Luo, Xiusong Pan, Jianfeng Chen   +6 more
wiley   +1 more source

Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae

iMeta, EarlyView.
Transient exposure to ampicillin results in restructuring of microbiota to favor oxygen‐tolerant bacteria, whereas osmotic laxative perturbation preserves Bacteriodota. Ampicillin‐ but not laxative‐exposed environment favors establishment of rmpA phase variants that lost hypermucoviscosity but short‐chain fatty acids present in the laxative‐exposed gut
Carey Lim, Jialing Zheng, Guoxiang Cheam, Melvin Yong, Hanrong Chen, Andrew Ting, Yahua Chen, Qingqing Wang, Niranjan Nagarajan, Yunn‐Hwen Gan   +9 more
wiley   +1 more source

A talus rock glacier in Nantlle Valley, North Wales

Journal of Quaternary Science, EarlyView.
ABSTRACT Landforms comprising mixtures of fine and coarse sediment and deposited during late glacial times are ubiquitous in the British mountains. In many cases, their interpretation has often proved contentious; as a result, the non‐generic term discrete debris accumulations (DDA) has been used to describe them and, over the last 50 years, some have ...
Stephan Harrison, Ed Anderson
wiley   +1 more source

Evaluation of methods for the analysis of oxygen and carbon dioxide in water, sediment, litter, and soil

Limnology and Oceanography: Methods, EarlyView.
Abstract Choosing an appropriate analyzer to measure concentrations of oxygen (O2) and carbon dioxide (CO2) during biogeochemical cycling studies can be difficult, considering the range of options available. While several studies examine the abilities of specific analyzers, comparison of multiple analyzers and environmental sample types is lacking.
Elizabeth Jakobsson, Konstantinos‐Marios Vaziourakis, Lars Tranvik   +2 more
wiley   +1 more source

Phosphorus limits the growth of bacterial and eukaryotic primary producers in recently deglaciated High Arctic soils

Oikos, EarlyView.
Glaciers are receding at unprecedented rates worldwide, exposing large areas of barren sediment that are quickly colonized by microbes. Nutrient availability is a critical driver of early ecosystem succession, but in the High Arctic its role has remained uncertain.
Steven K. Schmidt, Jannetta N. Robinson, Adam J. Solon, James A. Bradley, Anastasia S. Hambi, Rachel R. Rubin, Charles Oliver, Ben W. Johnson, Mihai O. Cimpoiasu, Trevor P. Irons, Oliver Kuras, Anna Bergstrom, Pacifica Sommers   +12 more
wiley   +1 more source

Using participatory scenario planning to explore the synergies and trade‐offs from upland treescape expansion

People and Nature, EarlyView.
Abstract The future of land use in the UK uplands is highly debated, with growing interest in increasing tree cover and other land use changes, alongside a desire to maintain traditional land use patterns and practices. Treescape expansion is likely to result in synergies and trade‐offs between different outcomes, so integrating stakeholder preferences
Melissa Minter, Susan Baker, Euan Bowditch, Sheena Carlisle, Natasha Constant, Alix Syder, Tom Finch   +6 more
wiley   +1 more source

Rewilding's technological experiments: Virtual reality and scalable narratives of rewilding in the Scottish highlands

People and Nature, EarlyView.
Abstract Depictions of rewilded landscapes reveal the underlying principles shaping the future of rewilding. This paper analyses a virtual reality (VR) model of a rewilding project in the Scottish Highlands that is advertised as a vision of a rewilded nature in 50 to 100 years' time.
Nick Sidwell
wiley   +1 more source