Results 161 to 170 of about 94,466 (297)

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

open access: yesThe FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi   +12 more
wiley   +1 more source

Evolving treatments for Sjögren disease: current approaches and emerging targets

open access: yesInternal Medicine Journal, EarlyView.
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani   +3 more
wiley   +1 more source

Bradycardia in a woman

open access: yesJACEP Open
Fang‐Yu Lin   +2 more
openaire   +3 more sources

Impact of Emergent Physician Notifications from Mobile Cardiac Outpatient Telemetry on Patient Outcomes (The EP‐COT Trial)

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction Mobile ambulatory cardiac telemetry (MCOT) use has increased over time; however, data on the prevalence and the impact of emergent arrhythmia notifications with MCOT remains unclear. We sought to determine the prevalence and clinical impact of emergent arrhythmia events in patients undergoing MCOT monitoring.
David Lin   +11 more
wiley   +1 more source

Impact of Left Bundle Branch Area Pacing on Echocardiographic Parameters and Symptoms: Data From the Conduction System Pacing Italian Network Group (C‐SING) Study

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
Left bundle branch area pacing is associated with preservation of ventricular function in patients with bradycardia indications and with significant reverse remodeling and symptomatic improvement in patients with heart failure. Maintaining a high percentage of effective LBBAP capture is critical to minimize the risk of pacing‐induced cardiomyopathy and
Gabriele Dell'Era   +32 more
wiley   +1 more source

Left Bundle Branch Area Pacing versus Deep Septal Pacing in Patients After Transcatheter Aortic Valve Replacement

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Left bundle branch area pacing (LBBAP) has been reported to improve long‐term clinical outcomes in patients requiring permanent pacemaker implantation (PPMI) after transcatheter aortic valve replacement (TAVR). Deep septal pacing (DSP) has emerged as a potential alternative to LBBAP.
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

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