Results 161 to 170 of about 180,641 (332)

Economic evidence for licensed ready‐to‐administer intravenous products compared with standard vials and ampoules: a systematic review

Anaesthesia, EarlyView.
Summary Introduction Injectable medicines represent a significant proportion of the annual medicines expenditure of the NHS in England, totalling £7 billion ($9.4 billion, €8.0 billion) in 2023. This represents approximately 70% of hospital medicines spending and includes essential treatments delivered at the point of care, such as chemotherapy ...
Suzanne Al‐Rawi, Matthew Greening, Sue Ladds   +2 more
wiley   +1 more source

Critical care delirium: prevention, identification and management: a narrative review

Anaesthesia, EarlyView.
Summary Introduction Delirium is a frequent complication of critical illness and remains an important cause of short‐ and long‐term morbidity for patients admitted to ICUs. Delirium is associated with prolonged mechanical ventilation; extended ICU and hospital stay; and longer‐term health issues. Development is associated with patient (e.g.
Stephanie Kieswick, Ben Gibbison
wiley   +1 more source

Efficacy and safety of different vasopressor infusions on feto‐maternal outcomes in normotensive patients undergoing caesarean delivery: a systematic review and network meta‐analysis of randomised controlled trials

Anaesthesia, EarlyView.
Summary Introduction Phenylephrine infusion is widely endorsed by guidelines as the preferred prophylactic drug for spinal hypotension in patients undergoing caesarean delivery; however, clinical practice continues to show marked variability in the selection of vasopressor drugs.
Narinder Pal Singh, Jeetinder Kaur Makkar, Bisman Jeet Kaur Khurana, Anuradha Borle, Preet Mohinder Singh   +4 more
wiley   +1 more source

Discharging Preterm Infants on Caffeine—Practise Variation Across Europe: Results of a Cross‐Sectional Survey

Acta Paediatrica, EarlyView.
ABSTRACT Aim Caffeine is the mainstay of treatment for apnea of prematurity, yet the optimal strategy and timing for discontinuation remain undefined. Marked inter‐centre variation in the practise of discharging preterm infants home on caffeine therapy has been reported.
Martin Kuntz, Lina Raljevic, Katharina Bergmann, Daniel Matheisl, Hendryk Schneider, Hans Fuchs   +5 more
wiley   +1 more source

Features of cholinergic cardia regulation under conditions of hypokinesia [PDF]

The features of cholinergic processes in the heart on the 4th, 8th, 16th and 30th days of hypokinesia were studied in experiments on 382 albino rats.
Babinskaya, L. N., Bolyarskaya, V. A., Bondarenko, Y. I., Fayfura, V. V., Markova, Y. A., Rosolovskiy, A. P.   +5 more
core   +1 more source

CoolCuddle and Autonomic Regulation in Infants With Hypoxic‐Ischaemic Encephalopathy: An Intervention Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim We evaluated the impact of ‘CoolCuddle’, parental cuddling during therapeutic hypothermia intervention for hypoxic‐ischaemic encephalopathy, on heart rate variability (HRV). Methods In this prospective, single‐group, interventional study with repeated measures, we included infants ≥ 36 weeks' gestation undergoing hypothermia and CoolCuddle
Ela Chakkarapani, Satomi Okano, David Odd, CoolCuddle Study Investigators   +3 more
wiley   +1 more source

The first case of Reel Syndrome in a dog after pacemaker implantation: A case report

Australian Veterinary Journal, EarlyView.
Reel Syndrome is a rare complication of permanent pacemaker implantation, characterised by the rotation of the device around its transverse axis, which causes the lead to coil around the generator and displacement, leading to pacing dysfunction. This report presents the first documented case of Reel Syndrome in a dog.
Z Wojtczak, M Lewicki, M Płóciennik, J Gach, K Nowak, A Noszczyk‐Nowak   +5 more
wiley   +1 more source

Mad Honey Poisoning Presenting With Anaphylaxis and Cardiovascular Instability: A Case Series. [PDF]

Case Rep Med
Baral A, K C K.
europepmc   +1 more source

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia, Lisa Zimmer, Lena Lampe, Dimitra Vlachopoulou, Matthias Totzeck, Tienush Rassaf, Raluca I. Mincu   +6 more
wiley   +1 more source

Diltiazem N‐oxide, a novel ischaemia‐activated prodrug, prevents ischaemia‐induced ventricular fibrillation without off‐target adverse effects

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh, Gabriel A. Watson, Francesca Mazzacuva, Zoe Hoare, Thomas R. Eykyn, Michael J. Curtis   +5 more
wiley   +1 more source