Results 271 to 280 of about 136,691 (332)

Microelectrode recordings from the human cervical vagus nerve during maximal breath‐holds

open access: yesExperimental Physiology, EarlyView.
Abstract Voluntary breath‐holds can be sustained for a long time following training, but ultimately, regardless of duration, the asphyxic break‐point is reached and the apnoea terminated. The physiological changes occurring during the apnoea include a marked increase in sympathetically‐mediated vasoconstriction in non‐essential organs, such as skeletal
Vaughan G. Macefield   +7 more
wiley   +1 more source

Suppression of premature ventricular complexes with the PDE5 inhibitor sildenafil: First clinical experience

open access: yesExperimental Physiology, EarlyView.
Abstract The phosphodiesterase‐5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug‐induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing ‘R‐on‐T’ ventricular tachycardia.
David C. Hutchings   +3 more
wiley   +1 more source

Sinus bradycardia and acute renal injury secondary to Viperidae snakebite: first case report. [PDF]

open access: yesFront Med (Lausanne)
Guamán-Charco ED   +7 more
europepmc   +1 more source

Physiology of nitrogen: A life or death matter

open access: yesExperimental Physiology, EarlyView.
Abstract With each breath, four out of every five molecules we inspire are nitrogen (N2), since this gas constitutes ∼80% of the atmospheric air that surrounds us. Despite its abundance and unlike molecular oxygen, N2 has traditionally held less appeal among physiologists given its lack of reactivity and corresponding inability to support combustion or
Damian M. Bailey   +2 more
wiley   +1 more source

Sympathetic stimulation can compensate for hypocalcaemia‐induced bradycardia in human and rabbit sinoatrial node cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend AC: adenylyl cyclase, APT: adenosine triphosphate, AMP: adenosine monophosphate, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterase, PKA: protein kinase A, PPT: protein phosphatase, P: phosphorylation, RyR: ryanodine receptor, SERCA: sarcoplasmic/endoplasmic reticulum Ca2+‐adenosine triphosphatase, SR: sarcoplasmic ...
Moritz Linder   +4 more
wiley   +1 more source

Sex‐specific differences in mortality and neurocardiac interactions in the Kv1.1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP)

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The Kcna1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP) exhibits sex‐specific differences in SUDEP risk. Female mice exhibit a lower SUDEP risk than males, despite similar seizure characteristics and interictal cardiac function across sexes.
Kelsey Paulhus   +11 more
wiley   +1 more source

Managing Bradycardia in Patients After Transcatheter Tricuspid Valve Replacement. [PDF]

open access: yesStruct Heart
Hain A   +6 more
europepmc   +1 more source

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