Results 31 to 40 of about 62,576 (222)

Differences in Intersubject Early Readiness Potentials Between Voluntary and Instructed Actions

Frontiers in Psychology, 2020
Readiness potential (RP) is a slow negative electroencephalogram (EEG) potential prior to voluntary action and was first described by Kornhuber and Deecke (1965).
Lipeng Zhang, Lipeng Zhang, Rui Zhang, Rui Zhang, Dezhong Yao, Dezhong Yao, Li Shi, Li Shi, Jinfeng Gao, Jinfeng Gao, Yuxia Hu, Yuxia Hu   +11 more
doaj   +1 more source

An empirical comparison of deep learning explainability approaches for EEG using simulated ground truth

Scientific Reports, 2023
Recent advancements in machine learning and deep learning (DL) based neural decoders have significantly improved decoding capabilities using scalp electroencephalography (EEG). However, the interpretability of DL models remains an under-explored area. In
Akshay Sujatha Ravindran, Jose Contreras-Vidal   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A High-Quality and Robust Intravascular Electromyography (iEMG) Acquisition Method for Locomotor Tasks

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Electromyography (EMG) is essential in medical and rehabilitation fields for assessing neuromuscular functions. However, mainstream traditional surface EMG (sEMG) is susceptible to electrode displacement or noise interference during walking, leading to ...
Ying Du, Gan Liu, Yudong Ma, Sining Li, Yahan Duan, Wenzhi Wang, Feng Duan   +6 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Autism spectrum disorder disrupts brain network connectivity maturation during childhood development

Scientific Reports
Understanding the developmental trajectory of autism spectrum disorder (ASD) remains a critical barrier for timely intervention in children. Here, we investigated the deficit brain maturation trajectory during childhood development in 35 ASD level 1 and ...
Lattika Tiawongsuwan, Sumeth Klomchitcharoen, Wachiraya Chumanee, Tanchanok Tangwattanasirikun, Soracha Saksittikorn, Saharat Chawaruechai, Tirapoot Jatupornpoonsub, Yodchanan Wongsawat   +7 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

A wearable repetitive transcranial magnetic stimulation device

Nature Communications
Repetitive transcranial magnetic stimulation (rTMS) is widely used to treat various neuropsychiatric disorders and to explore the brain, but its considerable power consumption and large size limit its potential for broader utility, such as applications ...
Zihui Qi, Hao Liu, Fang Jin, Yihang Wang, Xuefeng Lu, Ling Liu, Zhengyi Yang, Lingzhong Fan, Ming Song, Nianming Zuo, Tianzi Jiang   +10 more
doaj   +1 more source

How Electroencephalogram Reference Influences the Movement Readiness Potential?

Frontiers in Neuroscience, 2017
Readiness potential (RP) based on electroencephalograms (EEG) has been studied extensively in recent years, but no studies have investigated the influence of the reference electrode on RP.
Yuxia Hu, Lipeng Zhang, Mingming Chen, Xiaoyuan Li, Li Shi   +4 more
doaj   +1 more source