Results 91 to 100 of about 3,807,772 (315)

Therapies for neonatal encephalopathy: Targeting the latent, secondary and tertiary phases of evolving brain injury

open access: yes, 2021
In term and near-term neonates with neonatal encephalopathy, therapeutic hypothermia protocols are well established. The current focus is on how to improve outcomes further and the challenge is to find safe and complementary therapies that confer ...
Newborn Brain Society Guidelines and Publications Committee
core  

How Does Max Brain Work?

open access: yes, 2022
Can anyone else feel the love for using this? Doing it needs more work. Finding it is not difficult. You would guess that they had a never ending supply. In a recent poll, more than half of all Italians disagreed.
Max Brain
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Augmented visualisation of tumour boundaries and functioning brain during neurosurgery

open access: yes
Introduction. Surgery for brain tumours represents a major and multidisciplinary challenge. An extensive body of literature suggests a non-linear correlation between the extent of resection and survival.
Anichini, Giulio
core   +1 more source

Implantable brain–computer interface for neuroprosthetic-enabled volitional hand grasp restoration in spinal cord injury

open access: yes, 2023
Loss of hand function after cervical spinal cord injury severely impairs functional independence. We describe a method for restoring volitional control of hand grasp in one 21-year-old male subject with complete cervical quadriplegia (C5 American Spinal ...
Dietrich, W Dalton   +22 more
core   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Altered caudate connectivity is associated with executive dysfunction after traumatic brain injury [PDF]

open access: yes, 2017
Traumatic brain injury often produces executive dysfunction. This characteristic cognitive impairment often causes long-term problems with behaviour and personality.
Niall J Bourke   +29 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

La segregación, los guetos y la integración social urbana: mitos y claves

open access: yesEURE (Santiago) - Revista Latinoamericana de Estudios Urbano Regionales, 2008
Predominan en el medio académico y político las nociones "naturalistas" sobre la segregación social del espacio en las ciudades latinoamericanas. Las desigualdades o el "clasismo", hechos fuertes y persistentes, harían de la segregación algo inevitable ...
FRANCISCO SABATINI, ISABEL BRAIN
doaj  

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