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Problems of Geroscience, 2023
Brain aging is part of the aging of the whole body, largely determining the success of general aging and the quality of life of an older person. Brain aging is a complex multifactorial process that occurs throughout a human’s life, which includes changes at subcellular, tissue, and organ levels as well as at physiological level, mediating changes in
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Brain aging is part of the aging of the whole body, largely determining the success of general aging and the quality of life of an older person. Brain aging is a complex multifactorial process that occurs throughout a human’s life, which includes changes at subcellular, tissue, and organ levels as well as at physiological level, mediating changes in
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ISMRM Annual Meeting, 2023
The structural brain-age makes predictions based on changes in tissue integrity. Adding cerebrovascular MRI biomarkers may add sensitivity to physiological and metabolic changes, hence complementing structural brain-age, and possibly improving its early pathology sensitivity.
Dijsselhof, M. B. J. +9 more
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The structural brain-age makes predictions based on changes in tissue integrity. Adding cerebrovascular MRI biomarkers may add sensitivity to physiological and metabolic changes, hence complementing structural brain-age, and possibly improving its early pathology sensitivity.
Dijsselhof, M. B. J. +9 more
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Acta Neurologica Scandinavica, 1992
A recent interest in aging of the nervous system is related to the remarkable increase in the numbers of elderly persons throughout the world. As a reflection of the added years, pathologies in the older person have also increased. Primary among those which affect the activities and behavior of these people are the dementias, especially Alzheimer's ...
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A recent interest in aging of the nervous system is related to the remarkable increase in the numbers of elderly persons throughout the world. As a reflection of the added years, pathologies in the older person have also increased. Primary among those which affect the activities and behavior of these people are the dementias, especially Alzheimer's ...
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Clinics in Geriatric Medicine, 1985
Changes in neurons, glial cells, synapse morphologic and electrophysiologic appearance, and neurotransmission mechanisms during normal aging are considered for review in this article. These processes not only are fundamental in the neurobiology of normal aging but also are implicated in the pathogenesis of aging.
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Changes in neurons, glial cells, synapse morphologic and electrophysiologic appearance, and neurotransmission mechanisms during normal aging are considered for review in this article. These processes not only are fundamental in the neurobiology of normal aging but also are implicated in the pathogenesis of aging.
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Age increases brain complexity
Electroencephalography and Clinical Neurophysiology, 1996This study investigated age-related changes in the human brain function using both traditional EEG analysis (power spectra) and the correlational dimension, a measure reflecting the complexity of EEG dynamics and, probably, the complexity of neurophysiological processes generating the EEG.
A P, Anokhin +4 more
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Current Opinion in Neurobiology, 2022
The aging brain is shaped by many structural and functional alterations. Recent cross-disciplinary efforts have uncovered powerful and integrated adaptive mechanisms that promote brain health and prevent functional decline during aging. Here, we review some of the most robust adaptive mechanisms and how they can be engaged to protect, and restore the ...
Liviu, Aron +2 more
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The aging brain is shaped by many structural and functional alterations. Recent cross-disciplinary efforts have uncovered powerful and integrated adaptive mechanisms that promote brain health and prevent functional decline during aging. Here, we review some of the most robust adaptive mechanisms and how they can be engaged to protect, and restore the ...
Liviu, Aron +2 more
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Neurology, 2022
The pandemic is transforming neurology. Long COVID will linger, neurologic diseases will increase, and technology, artificial intelligence, and new virtual worlds will usher a new age of the brain and new roles for neurologists. The pandemic has compelled international collaboration, greatly increased communications, and accelerated drug and vaccines ...
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The pandemic is transforming neurology. Long COVID will linger, neurologic diseases will increase, and technology, artificial intelligence, and new virtual worlds will usher a new age of the brain and new roles for neurologists. The pandemic has compelled international collaboration, greatly increased communications, and accelerated drug and vaccines ...
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Annals of Neurology, 1985
AbstractPostmortem and computed tomographic studies demonstrate many anatomical, morphological, and neurochemical differences between brains of old and young human beings. The variability of the results is great, however, and brains of some old subjects have characteristics of brains of younger controls.
H, Creasey, S I, Rapoport
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AbstractPostmortem and computed tomographic studies demonstrate many anatomical, morphological, and neurochemical differences between brains of old and young human beings. The variability of the results is great, however, and brains of some old subjects have characteristics of brains of younger controls.
H, Creasey, S I, Rapoport
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Pathophysiology of Ageing Brain
Gerontology, 1987Even in nonfamilial cases of dementia there is some evidence of a genetic factor. This may be linked to defective expression of neurofilament protein and also abnormal phosphorylation of cytoskeletal proteins. In this respect there may be a link with accumulation of tangles and amyloid which have some degree of homology.
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