Results 61 to 70 of about 2,163,819 (261)

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello   +10 more
wiley   +1 more source

Brain-wide cellular resolution imaging of Cre transgenic zebrafish lines for functional circuit-mapping

open access: yeseLife, 2019
Decoding the functional connectivity of the nervous system is facilitated by transgenic methods that express a genetically encoded reporter or effector in specific neurons; however, most transgenic lines show broad spatiotemporal and cell-type expression.
Kathryn M Tabor   +10 more
doaj   +1 more source

Northern Territory of South Australia [cartographic material]

open access: yes, 1886
Map of the Northern Territory showing places named after British Prime Ministers and parliamentarians. Relief shown by hachures.; Prime meridian: Greenwich.; From: Picturesque atlas of Australasia.
Picturesque Atlas Publishing Company.
core  

ATLAS Event Display: photonuclear collision

open access: yes, 2021
Event display of a photonuclear collision, where a high-energy photon strikes a lead nucleus, recorded by the ATLAS detector during 2018 Pb+Pb collision period.
ATLAS Collaboration
core  

Additively Manufactured Geometry‐Reconfigurable Soft Neural Probes With Monolithic Multifunctionality

open access: yesAdvanced Functional Materials, EarlyView.
A geometry‐reconfigured additive manufacturing strategy converts planar printed soft materials into soft compact neural probes with integrated hydrogel electrodes and microfluidic channels. The resulting NeuroMAP platform enables scalable multichannel recording, localized chemical delivery, stable in vivo electrophysiological recording, and reduced ...
Hyunjin Lee   +15 more
wiley   +1 more source

Use of brain MRI atlases to determine boundaries of age-related pathology: the importance of statistical method.

open access: yesPLoS ONE, 2015
IntroductionNeurodegenerative disease diagnoses may be supported by the comparison of an individual patient's brain magnetic resonance image (MRI) with a voxel-based atlas of normal brain MRI.
David Alexander Dickie   +4 more
doaj   +1 more source

An Adult Brain Atlas Reveals Broad Neuroanatomical Changes in Independently Evolved Populations of Mexican Cavefish

open access: yesFrontiers in Neuroanatomy, 2019
A shift in environmental conditions impacts the evolution of complex developmental and behavioral traits. The Mexican cavefish, Astyanax mexicanus, is a powerful model for examining the evolution of development, physiology, and behavior because multiple ...
Cody Loomis   +17 more
doaj   +1 more source

Railway, postal & telegraph map of Queensland 1888 [cartographic material] /

open access: yes, 1888
Map of Queensland showing railways, places with postal and telegraph services and average annual rainfall. Has index to towns.; Folded map from Vol. 2 of: Picturesque Atlas of Australasia. Sydney : Picturesque Atlas Publishing Company, Limited, 1886-1889.
Picturesque Atlas Publishing Company.
core  

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

open access: yesAdvanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu   +8 more
wiley   +1 more source

Sex-specific single transcript level atlas of vasopressin and its receptor (AVPR1a) in the mouse brain

open access: yeseLife
Vasopressin (AVP), a nonapeptide synthesized predominantly by magnocellular hypothalamic neurons, is conveyed to the posterior pituitary via the pituitary stalk, where AVP is secreted into the circulation.
Anisa Azatovna Gumerova   +18 more
doaj   +1 more source

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