Results 31 to 40 of about 65,253 (267)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Revisiting embodiment for brain–computer interfaces

Human–Computer Interaction, 2023
Researchers increasingly explore deploying brain-computer interfaces (BCIs) for able-bodied users, with the motivation of accessing mental states more directly than allowed by existing body-mediated interaction. This motivation seems to contradict the long-standing HCI emphasis on embodiment, namely the general claim that the body is crucial for ...
Serim, Barış, Spapé, Michiel, Jacucci, Giulio   +2 more
openaire   +4 more sources

Autism spectrum disorder disrupts brain network connectivity maturation during childhood development

Scientific Reports
Understanding the developmental trajectory of autism spectrum disorder (ASD) remains a critical barrier for timely intervention in children. Here, we investigated the deficit brain maturation trajectory during childhood development in 35 ASD level 1 and ...
Lattika Tiawongsuwan, Sumeth Klomchitcharoen, Wachiraya Chumanee, Tanchanok Tangwattanasirikun, Soracha Saksittikorn, Saharat Chawaruechai, Tirapoot Jatupornpoonsub, Yodchanan Wongsawat   +7 more
doaj   +1 more source

A High-Quality and Robust Intravascular Electromyography (iEMG) Acquisition Method for Locomotor Tasks

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Electromyography (EMG) is essential in medical and rehabilitation fields for assessing neuromuscular functions. However, mainstream traditional surface EMG (sEMG) is susceptible to electrode displacement or noise interference during walking, leading to ...
Ying Du, Gan Liu, Yudong Ma, Sining Li, Yahan Duan, Wenzhi Wang, Feng Duan   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A wearable repetitive transcranial magnetic stimulation device

Nature Communications
Repetitive transcranial magnetic stimulation (rTMS) is widely used to treat various neuropsychiatric disorders and to explore the brain, but its considerable power consumption and large size limit its potential for broader utility, such as applications ...
Zihui Qi, Hao Liu, Fang Jin, Yihang Wang, Xuefeng Lu, Ling Liu, Zhengyi Yang, Lingzhong Fan, Ming Song, Nianming Zuo, Tianzi Jiang   +10 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Low-power differencing feature extracts spiking-band activities for high-performance intracortical brain-computer interfaces

Communications Biology
Intracortical brain-computer interfaces (iBCIs) demand computationally efficient feature extraction methods to process high-bandwidth neural signals in resource-constrained implantable systems.
Guangxiang Xu, Chenbin Yu, Gengrong Shao, Gang Pan, Yueming Wang, Yaoyao Hao   +5 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

How Electroencephalogram Reference Influences the Movement Readiness Potential?

Frontiers in Neuroscience, 2017
Readiness potential (RP) based on electroencephalograms (EEG) has been studied extensively in recent years, but no studies have investigated the influence of the reference electrode on RP.
Yuxia Hu, Lipeng Zhang, Mingming Chen, Xiaoyuan Li, Li Shi   +4 more
doaj   +1 more source