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The Concept of Death and Deceased Organ Donation
An individual who has sustained either irreversible cessation of circulatory and respiratory functions, or irreversible cessation of all functions of the entire brain, including the brainstem is dead. A person is not dead unless his brain is dead.
Francis Delmonico
doaj
Increasing violent deaths and organ transplantation in Brazil: is there a parallel?
Mortality from violent causes has significantly increased in Brazil, as well as the number of deceased-donor organ transplantation. Although the increase in the number of transplants correlates with higher organ availability, through the increase in ...
Juliana Gomes Ramalho de Oliveira +3 more
doaj +1 more source
rans Plantation of origans of Brain Deads in Islamic law (1379) [PDF]
The soul does its duties by brain which are foresight and manipulation, therefore at the time of death, the soul leaves the body. There is difference between death of organs and the whole body, because some organs are still alive after death.
Ali Asghar Hatami, Neda masodi
doaj
QUESTION UNDER STUDY: For the determination of brain death (BD) in potential organ donors, confirmatory tests that show cessation of cerebral circulation are used in many countries.
A Rieke, C Ozdoba
doaj +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Se hizo una revisión sobre la aplicación de los potenciales evocados multimodales (PEM) para la neuromonitorización del coma, y como pruebas confirmatorias, en el diagnóstico de la muerte encefálica (ME). Los resultados presentados demuestran el valor de
Calixto Machado Curbelo +4 more
doaj
Iowa Plan for Brain Injury, October 2002 – September 2005 [PDF]
Cutting edge emergency services now allow many Iowans to survive a traumatic brain injury (TBI) that would have caused death just a decade ago.
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