Acanthamoeba castellanii induces host cell death via a phosphatidylinositol 3-kinase-dependent mechanism [PDF]
Granulomatous amoebic encephalitis due to Acanthamoeba castellanii is a serious human infection with fatal consequences, but it is not clear how the circulating amoebae interact with the blood-brain barrier and transmigrate into the central nervous ...
Alsam, S. +5 more
core +3 more sources
Organ and tissue donation is defined as the transfer of human cells, tissues and organs from a donor to a recipient; it is the only therapeutic option that helps to improve the quality of life and prevent the death of people with tissue or organ failure.
Karla Jiménez Oliver
doaj +1 more source
Microglia-derived microvesicles affect microglia phenotype in glioma [PDF]
Extracellular-released vesicles (EVs), such as microvesicles (MV) and exosomes (Exo) provide a new type of inter-cellular communication, directly transferring a ready to use box of information, consisting of proteins, lipids and nucleic acids.
Alfonso Grimaldi +14 more
core +5 more sources
Diseased Organ and tissue donation and transplantation entails removing organ and tissues from someone (the donor) and transplanting them into another person (the recipient).
Mohammad Abdus Sayek Khan
doaj +1 more source
TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death [PDF]
Newborn mice carrying targeted mutations in genes encoding neurotrophins or their signaling Trk receptors display severe neuronal deficits in the peripheral nervous system but not in the CNS. In this study, we show that trkB (¿/¿) mice have a significant
Alcántara Horrillo, Soledad +5 more
core +1 more source
Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]
Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh +5 more
core +1 more source
Benefits of hypertonic saline for cardiothoracic organ transplantation with brain death donors. [PDF]
Correia CJ +2 more
europepmc +2 more sources
Biological Principles in Self-Organization of Young Brain - Viewed from Kohonen Model [PDF]
Variants of the Kohonen model are proposed to study biological principles of self-organization in a model of young brain. We suggest a function to measure aquired knowledge and use it to auto-adapt the topology of neuronal connectivity, yielding ...
A. De Angelis +7 more
core +2 more sources
Knowledge and attitudes toward brain death and organ donation in Bojnurd [PDF]
دانش و نگرش مردم شهر بجنورد (خراسان شمالی) در باره مرگ مغزی و اهدای ...
Hejazi, Sima Sadat +2 more
core +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source

